Top 10 Best flea and tick spray in 2026

Last Updated - 6/9/2026

🏆Best Choice

PetArmor

PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
•TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
•BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.
•FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months.
•EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with three (3) waterproof topical applications that provides your pet flea protection and control for three (3) months.

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$24.99

$28.99

-14%

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Adams

Adams Flea & Tick Home Spray with Precor, Kills Fleas, Flea Eggs, Flea Larvae, Bed Bugs, Ticks, Ants, Cockroaches, Spiders, Mosquitoes and Many Other Listed Nuisance Pests in The Home, 24 Fl Oz

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•PROVEN EFFECTIVE - Kills fleas, flea eggs, flea larvae, bed bugs, ticks, cockroaches, ants*, spiders, mosquitoes, and many other labeled insects (*except carpenter, harvester, pharaoh, and fire ants) on contact
•KILLS FAST - Begins killing fleas in as little as 5 minutes
•DUAL ACTION - Kills over 30 insects and prevents new infestations
•7-MONTH PROTECTION - Provides up to 7 months of flea protection
•COMPLETE HOME DEFENSE - Use on carpets, rugs, upholstery, and pet bedding; do not spray directly on pets
•EASY TO USE - Even and controlled spraying pattern for optimal results; this spray is not designed to be used directly on your pet
•FRAGRANCE FREE - Dries fast, non-staining, and no lingering odor
•PERFORMANCE PROVEN - Since 1975, Adams products offer a unique approach to prevention and protection for flea and tick control that you can rely on
•PET, HOME, AND YARD - 5% of fleas live on your pet while the remaining 95% live in your home or yard; complete your flea and tick control system with Adams Pet, Home, and Yard products
•FOR BEST RESULTS - Multiple steps or products may be necessary to help fight fleas and ticks on your pet - scroll down to view our comprehensive line of products
•Kills fleas, ticks, cockroaches, ants, spiders, mosquitoes, and many other insects
•For home use only
•Starts killing in 5 minutes
•Up to 7 months protection
•Convenient trigger sprayer

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Wondercide

Wondercide - Flea, Tick & Mosquito Spray for Dogs, Cats, and Home - Tick Killer, Control, Prevention, Treatment - with Natural Essential Oils - Pet and Family Safe - Cedarwood 16 oz

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•KILLS & REPELS. Using natural essential oils, this spray is proven to kill by contact, repel, and prevent 98-100% of fleas, ticks and mosquitoes in laboratory testing. It breaks the flea life cycle by eliminating eggs, larvae, and adults.
•TREAT NATURE WITH NATURE. When used as directed, a safe and effective alternative to collars, pills, chewables, and drops harnesses the power of nature. Holistic vet approved. Enjoy peace of mind knowing your pets and home are protected with our non-harsh formula.
•SAFE FOR DOGS, CATS OF ALL AGES WHEN USED AS DIRECTED. Gentle enough to use on puppies, kittens, and senior pets when used as directed. Powerful enough to fully eliminate pests on the skin and fur. Safe to use around the entire family, and kid-safe, when used as directed. Mom owned, Mom approved.
•3-IN-1 PLANT POWERED SOLUTION. For dogs, cats, and home! A home remedy that kills fleas throughout the house on carpet, furniture, bedding, and flooring. Also a repellent in pet environments like dog kennels or cat condos. Invigorating Cedar scent freshens homes.
•POWERFULLY EFFECTIVE. Powered by nature and proven to work. Give your pet the advantage in protection against fleas and ticks with our non-harsh formula. Cruelty free and USA Made with U.S. and global components. Read entire label prior to use. Do not soak pet. Test a small area on the back of the neck 1 hour prior to full body application.

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$26.99

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K9 Advantix

K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
•Kills fleas within 12 hours of application
•Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
•Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
•No prescription needed

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PetArmor

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•FAST-ACTING: One oral flea tablet starts killing fleas within 30 minutes of administration.
•SAFE TO USE: This oral flea medication is safe for puppies, dogs, cats, and kittens from 25lbs. and over, when used as directed.
•TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas simply apply another dose as often as once a day. CapAction Flea Pills are even safe for use on pregnant or breeding dogs.
•EASY TO USE: Without the mess and rubbing off of a flea and tick topical treatment and without the need of a veterinarian prescription this dog flea tablet is administered orally to kill adult fleas fast.
•KILL FLEAS EFFICIENTLY: CapAction flea treatment has 6 doses and kills adult fleas that may cause allergy dermatitis.

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$27.99

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Frontline

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
•Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
•Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
•FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
•Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
•Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
•Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

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$39.98

$44.99

-11%

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Vet's Best

Vet’s Best Indoor Flea and Tick Spray – Dog Flea and Tick Treatment for Home, Plant-Based Formula with Natural Oils, Kills Fleas, Eggs & Ticks on Contact, Made in USA, 32 oz

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•FLEA & TICK FIGHTER: Say goodbye to fleas, larvae, eggs, ticks, and mosquitoes with our natural flea and tick spray. It eliminates existing infestations and helps protect against future pests—keeping your dog and home safe and comfortable.
•FLEA & TICK SPRAY FOR HOME & DOG: Our flea and tick spray for dogs is gentle enough to use on dogs 12 weeks or older and can be applied directly to their skin; it's the perfect flea spray for carpet and furniture as it will not leave any stains or residue
•CERTIFIED NATURAL: Our flea & tick spray for dogs uses certified natural plant-based ingredients like peppermint oil and eugenol, keeping your dog safe from harsh chemicals; this flea spray leaves a pleasant scent that will have your dog feeling refreshed
•PROVEN EFFECTIVE: Our flea and tick spray is scientifically proven to be effective in killing and repelling fleas, ticks, and mosquitoes; with its powerful formulation, you can trust it to provide reliable and long-lasting protection for your furry friend
•MADE IN THE USA: Proudly manufactured in the USA using high-quality domestic and globally sourced ingredients. This flea and tick spray is vet-formulated for safety, effectiveness, and peace of mind—designed to protect pets and your home naturally.

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$15.48

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Hartz

Hartz UltraGuard Dual Action Flea & Tick Topical Dog Treatment and Flea and Tick Prevention, 6 Months, 5-14 Pound Dogs 6-count(Pack of 1)

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•KILLS FLEAS & TICKS: Kills fleas, flea eggs, deer ticks, and brown dog ticks on contact – it is important for your pup to have a flea and tick prevention treatment all year round!
•PREVENTS RE-INFESTATION: This topical formula prevents re-infestation by breaking the flea life cycle for up to 30 days.
•FAST ACTING FULL BODY PROTECTION: Active ingredients spread across the skin using your dog’s natural oil to quickly travel across the coat for full body protection from head to tail.
•6 MONTHLY FLEA & TICK TREATMENTS: Contains 6 single dose tubes (1 tube per monthly application) for non-stop protection for up to 6 months. Apply at the base of your dog’s back between the shoulder blades each month.

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$12.34

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Advantage

Advantage Dog Flea Treatment Spray | Kills Fleas & Ticks | Dog Flea Spray | 15 oz.

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Advantage Treatment Spray is a dog flea and tick treatment that kills and repels fleas, ticks and lice
•Delivers a whisper-quiet, continuous spray to provide 360-degree coverage while reducing stress to your dog
•Kills preadult fleas and flea eggs to prevent them from growing and becoming capable of biting
•Effective flea spray for dogs over 6 months old
•Use as part of a complete dog flea treatment program - killing pests on your pets and in your home and yard with Advantage products

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$19.98

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Vet's Best

Vet's Best Natural Flea and Tick Spray for Dogs – Plant-Based Flea Repellent with Certified Essential Oils – Natural Pest Control and Prevention – Non-Toxic Formula for Home Use – 8 oz Bottle

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•CONVENIENT 8 OZ BOTTLE: Protect your dog from fleas, ticks, and mosquitoes with our convenient 8-ounce flea and tick spray for dogs; our spray provides effective flea and tick prevention, making it an essential addition to your pet care routine
•PROVEN EFFECTIVE: Our flea spray for dogs is formulated with premium ingredients that have been rigorously tested for safety and effectiveness, so you can trust that you're providing your furry friend with the best possible flea and tick treatment
•CERTIFIED NATURAL: Our flea & tick spray for dogs uses certified natural plant-based ingredients like peppermint oil and eugenol, keeping your dog safe from harsh chemicals; this flea spray leaves a pleasant scent that will have your dog feeling refreshed
•GENTLE ON SKIN: Gentle on your pet's skin and coat, our tick spray is formulated for dogs and puppies 12 weeks or older; mild enough to use on even the most delicate skin types
•MADE IN THE USA: Our flea and tick spray is proudly manufactured in the USA with quality domestic and internationally sourced ingredients; made with the highest level of efficacy and safety with your beloved pet in mind

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$8.73

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