Top 10 Best eye saline in 2026

Last Updated - 6/12/2026

🏆Best Choice

Refresh

Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
•MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
•CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
•GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
•PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.

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$13.59

$15.75

-14%

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PhysiciansCare

PhysiciansCare Eye Wash Solution, Sterile Isotonic Buffered Solution for Flushing & Irrigating Eyes, 16-oz Bottle

9.6

ChoiceComparer.com Score

9.6

/ 10

Outstanding

Main highlights

•Flush Eye Irritants: This sterile buffered eye solution provides instant relief by flushing and irrigating the eyes; Bottle is for single use only
•Multipurpose Eye Rinse: Use our sterile isotonic buffered eye flush solution to rinse the eyes
•Clear Foreign Material From Eyes: Remove dust, pollen, chemicals or dirt with the help of this specifically formulated sterile eye wash
•Eye Application: Squeezable eye wash bottle allows you to direct a steady stream of solution directly onto the affected areas
•Stay Prepared: Keep this eye care solution on hand to quickly flush out any foreign substances that may accidentally enter your eyes

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$11.31

$19.11

-41%

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Bausch + Lomb

Sensitive Eyes Saline Solution from Bausch & Lomb, for Soft Contact & Gas Permeable Lenses, Saline Solution with Potassium, 2 x 12 Fl Oz (710 mL)

9.4

ChoiceComparer.com Score

9.4

/ 10

Outstanding

Main highlights

•Use for rinsing after daily cleaning and before insertion
•Safe for rinsing before or after heat, chemical, or hydrogen peroxide disinfection
•Use for diluting enzymatic cleaning tablets and storing soft contact lenses after thermal disinfection
•For over 150 years, Bausch + Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more
•Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to help your eyes feel moisturized & protected

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$9.79

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Fendall

Fendall Eyesaline Eyewash Saline Solution Bottle Refill, 32 oz (2 Pack)

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Brand: Fendall
•Fendall Eyesaline Eyewash Saline Solution Bottle Refill, 32 oz (2 Pack)

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$37.00

$39.99

-7%

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PhysiciansCare

PhysiciansCare by First Aid Only 7-006 Eye Wash Solution, 4 oz Bottle

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•Eye Flushing Solution for Irrigating the EPortable.
•Sterile isotonic buffered solution is perfect for flushing or aerating the skin.
•Sterile bottles, single use recommended.
•Great to keep on hand for eye irritation on the job.
•Great to use to irrigate the skin as well as the eyes

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$3.19

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RUGBY LABORATORIES

Rugby Sodium Chloride Hypertonicity Ophthalmic Eye Solution 5% - Sodium Chloride Eye Drops for Temporary Corneal Edema Relief - Alcohol-Free - 0.5 Fl. Oz. - 1 Pack

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•CORNEAL EDEMA SYMPTOM SUPPORT: Introducing Rugby Sodium Chloride Hypertonicity eye drops, a remedy that may help reduce symptoms of corneal edema.
•INGREDIENTS: Our formula is made with 5% sodium chloride, a hypertonicity agent. It is free from alcohol, soy, sugar, latex, gluten, and peanuts.
•QUALITY FORMULATION: We maintain high standards of care through strict regulatory compliance to deliver carefully formulated, effective eye drops. With a 5% sodium chloride formula, our solution may help to provide temporary relief from symptoms of corneal edema.
•HOW TO USE: Instill 1 or 2 drops of our solution into the affected eye(s) every 3 or 4 hours or as directed by a physician. It may cause temporary burning or irritation when used. Stop use if the condition persists for more than 72 hours.
•RUGBY LABORATORIES: At Rugby Laboratories, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering quality OTC and vitamin supplements.

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$16.45

$17.95

-8%

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Fendall

Honeywell Personal 16 oz. (473 ml) Trilingual Sterile Saline Eye Wash Bottle with Extended Flow Nozzle - 32-000454-0000-H5

8.7

ChoiceComparer.com Score

8.7

/ 10

Good

Main highlights

•SECONDARY EYE WASH: Support unit for immediate treatment while en route to primary eye wash station; buffered, sterile saline eye wash solution is superior to tap water which may contain contaminants
•EXTENDED FLOW NOZZLE: 16 oz. (473 ml) bottle features an extended-flow nozzle to provide longer flow than conventional 16 oz. containers
•TAMPER-RESISTANT: Blow-fill-seal bottles feature a tamper-resistant cap to ensure quality and safety of the eye wash solution; easily removed in an emergency
•ENSURED QUALITY: Ensured quality and lasting value with FDA-grade polyethylene eye wash bottles featuring lot numbers and expiration dates
•TRILINGUAL INSTRUCTIONS: Simple, highly visible instructions in English, Spanish & French are provided on each bottle;

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$16.88

$26.61

-37%

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Bausch + Lomb

Sensitive Eyes Saline Solution from Bausch & Lomb, for Soft Contact & Gas Permeable Lenses, Saline Solution with Potassium, 12 Fl Oz (355 mL)

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•Use for rinsing after daily cleaning and before insertion
•Safe for rinsing before or after heat, chemical, or hydrogen peroxide disinfection
•Use for diluting enzymatic cleaning tablets and storing soft contact lenses after thermal disinfection
•For over 150 years, Bausch + Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more
•Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to help your eyes feel moisturized & protected

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$5.51

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With our cutting-edge technology, we examine thousands of products and retailers, assessing reviews, ratings, trends, and sales rankings to identify what matters most to users like you.

Our team evaluates this data alongside genuine user feedback, merging AI analysis with human insights to provide you with real-time, highly-rated recommendations that empower your decision-making with clarity and confidence.