Top 10 Best neosporin cream in 2026

Last Updated - 6/23/2026

🏆Best Choice

neosporin

Neosporin Original First Aid Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes and Burns,.5 oz

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•.5-ounces of Neosporin Original Topical Antibiotic Ointment by the #1 doctor recommended brand for treating minor cuts, scrapes and burns
•Wound care ointment is formulated with neomycin sulfate, bacitracin zinc and polymyxin B antibiotic ingredients to provide 24-hour infection protection for minor wounds
•Topical first-aid ointment nourishes skin to minimize the appearance of scars after healing
•Contains HeliDerm Technology that provides a nourishing environment for skin to heal, resulting in healthier looking skin after use
•To use, apply a small amount of the first-aid antibiotic ointment to the affected area one to three times daily. Cover the wound with a Band-Aid Brand Adhesive Bandage for extra protection

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$4.88

$6.74

-28%

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Neosporin

Neosporin Original First Aid Triple Antibiotic Ointment, Bacitracin Zinc & Neomycin Sulfate Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes & Burns, 1 oz

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Triple antibiotic protection: Formula combines neomycin sulfate, bacitracin zinc, and polymyxin B antibiotic ingredients for 24-hour infection protection in minor cuts, scrapes, and burns; HeliDerm Technology nourishes skin for healthier healing
•Gentle non-greasy application: Topical antibiotic ointment absorbs quickly with no excessive oily residue for comfortable wear; versatile antibiotic action soothes, heals, and protects multiple minor wounds for long-lasting infection protection
•Scar minimizer: HeliDerm Technology provides a nourishing environment that lock in moisture to support natural skin repair and reduce scar appearance after healing; from the #1 doctor-recommended brand for reliable topical antibiotic ointment results
•Multi-use wound care: Ideal for minor cuts, scrapes, and burns; apply a small-sized dab one to three times daily and cover with a BAND-AID Brand sterile bandage for extra protection, supporting continuous 24-hour infection protection and healing
•Portable convenience: Neosporin Original 1 oz tube is compact for home, travel, and first aid kits; trusted triple antibiotic ointment formula by Kenvue delivers dependable infection protection wherever and whenever you need it

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$8.48

$8.99

-6%

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Neosporin

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Wound Care of Minor Cuts, Scrapes and Burns, Polymyxin B & Pramoxine HCl, 1 oz

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Antibiotic cream: Neomycin sulfate and polymyxin B sulfate deliver dual antibiotic action with up to 24-hour protection in a first-aid cream, helping prevent infection from minor cuts, scrapes, and burns when used as directed
•Pain relief analgesic: Pramoxine HCl provides maximum-strength pain relief as an external analgesic in a non-greasy, stain-free, no-sting formula that soothes discomfort from minor scrapes, burns, and cuts
•First-aid cream convenience: Includes one 1 oz tube (sold individually) for easy portability in backpacks, purses, and travel kits; apply one to three times daily after cleansing the affected area for straightforward, on-the-go wound care
•Sting-free formula: Fragrance-free, Neosporin + Pain Relief Dual Action Antibiotic Cream applies to skin easily, absorbs quickly without residue, and won't stain fabrics, supporting comfortable daily wound care for minor cuts, scrapes, and burns
•Complete wound care: Dual-action antibiotic cream and external analgesic help prevent infection for 24-hour protection and soothe pain in minor wounds; pair with a BAND-AID Brand sterile bandage after application for best results in first-aid kits

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$9.88

$12.39

-20%

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Neosporin

Neosporin + Pain Relief Dual Action Cream, .5 Oz

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•Soothing infection protection
•Maximum strength pain relief
•Helps prevent infection and provides pain relief
•Number-one doctor-recommended brand

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$5.98

$8.35

-28%

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Neosporin

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic & Analgesic for Wound Care of Minor Cuts, Scrapes & Burns, Polymyxin B & Pramoxine HCl, 1 oz, 2 Pack

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Twin pack containing two tubes of 1-ounce each of Neosporin + Pain Relief Dual Action Antibiotic Cream for first aid wound care of minor cuts, scrapes, and burns
•Topical antibiotic cream provides infection protection of minor wounds and helps to soothe and reduce pain with a maximum-strength, no-sting formula
•Contains both neomycin sulfate and polymyxin B sulfate antibiotics to help prevent wound infection of minor cuts, scrapes and burns and pramoxine hydrochloride as an external analgesic for maximum-strength pain relief
•The dual-action cream from the #1 doctor recommended brand not only helps fight infection for 24 hours, but also soothes & reduces pain, making it a great addition to your first-aid kit and wound care supplies
•For best results, clean the affected area, apply a small amount of the topical antibiotic and pain relief cream 1 to 3 times daily, and cover with a sterile bandage

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$17.78

$23.95

-26%

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Globe Pharmacy

(4 Pack) Globe Dual Action First Aid Antibiotic Cream + Pain Relief, Neomycin, Polymyxin B, Pramoxine HCl, Soothes Painful Cuts, Burns and Scrapes, 24 Hour Infection Protection

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•FIRST AID ANTIBIOTIC + PAIN RELIEF CREAM: Globe First Aid Cream with Pain Relief provides a maximum strength topical solution for minor cuts, burns, and scrapes. This powerful first aid cream protect against infections and soothe painful wounds for up to 24 hours.
•ACTIVE INGREDIENTS FOR INFECTION CARE: Formulated with Neomycin, Polymyxin B, and Pramoxine HCl, this first aid antibiotic cream offers strong, fast relief. It provides powerful protection against skin infections while offering pain relief, making it an essential addition to any first aid or medical kit for emergency care.
•TRAVEL-SIZE CONVENIENCE: Globe First Aid Antibiotic Cream comes in a portable, travel-size tube, perfect for on-the-go use. Keep it in your first aid cabinet, travel bag, car, or camping gear. Its compact size makes it ideal for quick first aid therapy wherever you are—home, work, or outdoors.
•MAXIMUM STRENGTH PROTECTION: This First Aid antibiotic and pain relief cream is designed to offer maximum strength protection for wounds, burns, and scrapes. It helps clean, protect, and soothe injured skin while providing lasting relief from pain and irritation.
•PHARMACEUTICAL-GRADE QUALITY: Manufactured to the highest pharmaceutical standards, Globe Triple Antibiotic Cream + Pain Relief ensures reliable infection protection. Each tube is formulated for safe use, and is packaged with an NDC code for added confidence in its medical-grade care.

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$12.99

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Neosporin

Neosporin First Aid Antibiotic Pain-Relieving, Anti-Itch, & Scar Ointment with Neomycin, Bacitracin Zinc, Pramoxine HCl & Polymyxin B, for Minor Cuts, Scrapes & Burns, 1 oz

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•1-ounce tube of Neosporin Pain, Itch & Scar First Aid Antibiotic Ointment from the number-one doctor recommended brand, helps protect and treat minor cuts, scrapes, and burns
•This topical antibiotic ointment contains bacitracin zinc, neomycin sulfate, and polymyxin B sulfate in a white petrolatum base to provide powerful 24-hour protection against infections
•The no-sting, anti-itch ointment formula also offers maximum strength pain and itch relief with the topical analgesic, pramoxine HCl
•The scar ointment features Heliderm technology that provides a nourishing environment for the skin during healing and minimizes the appearance of scars for healthier looking skin. This antibiotic ointment is great for your home first aid kit
•To use, apply a small amount of the analgesic skin ointment to the affected area one to three times daily. Cover the treated wound with a Band-Aid Brand Adhesive Bandage for proper protection

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$10.98

$14.72

-25%

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Neosporin

Neosporin + Lidocaine First Aid Antibiotic Ointment, Maximum Strength & Fast-Acting Topical Pain Reliever, 24-Hour Infection Protection That Numbs Away The Pain, Bacitracin Zinc, 0.5 oz

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•0.5-ounce tube of Neosporin + Lidocaine Pain Relieving Antibiotic Ointment for first aid wound care of minor cuts, scrapes, and burns
•Topical antibiotic ointment provides 24-hour infection protection of minor wounds and helps to reduce pain with maximum-strength, fast-acting lidocaine to numb the area
•Contains bacitracin zinc, neomycin sulfate and polymyxin B sulfate antibiotics to help prevent wound infection of minor cuts, scrapes, and burns and fast-acting lidocaine as an external analgesic for maximum-strength numbing and pain relief
•The antibiotic ointment from the #1 doctor recommended brand not only helps fight infection for 24 hours, but also numbs away the pain, making it a great addition to your first-aid kit and wound care supplies
•For best results, clean the affected area, apply a small amount of the topical antibiotic and pain relief numbing ointment 1 to 3 times daily, and cover with a sterile bandage

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$8.49

$11.11

-24%

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Band-Aid

Band-Aid Brand Adhesive Bandages Infection Defense with Neosporin Antibiotic Ointment, Pack of Assorted Sizes, for Wound Care and First Aid, 20 ct

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•20-sterile bandages in assorted sizes, Band-Aid Brand Adhesive Bandages Infection Defense with Neosporin
•Antibiotic ointment on the pad for, no-mess infection protection
•4-sided seal protects against dirt & germs that may cause infection & delay healing
•Hurt-Free Pad won't stick to the wound, allowing for gentle removal of the adhesive bandage
•Apply bandage to clean, dry skin for first aid of minor cuts, scrapes and burns, replacing as needed

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$3.77

$4.29

-12%

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Neosporin

Neosporin Antibiotic Pain-Relieving, Anti-Itch, & Scar Appearance Minimizer Ointment with Neomycin & Bacitracin Zinc, 24-Hour Infection Protection for Minor Cuts, Scrapes & Burns,.5 oz

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•.5-ounce tube of Neosporin + Pain, Itch, Scar Antibiotic Ointment from the number-one doctor recommended brand, helps protect and treat minor cuts, scrapes, burns, and wounds
•This topical antibiotic ointment contains the infection-fighting antibiotic ingredients bacitracin zinc, neomycin sulfate, and polymyxin B sulfate in a white petrolatum base to provide powerful 24-hour infection protection
•The no-sting, anti-itch ointment formula also offers maximum strength pain and itch relief with the external analgesic, pramoxine HCl
•The scar-minimizing ointment features Heliderm technology that provides a nourishing environment for the skin during healing and minimizes the appearance of scars for healthier looking skin
•To use, clean the affected area and apply a small amount of the first-aid antibiotic skin ointment one to three times daily. Cover the treated wound with a Band-Aid Brand Adhesive Bandage for proper wound care and protection.

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$8.28

$11.11

-25%

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