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    ChoiceComparer.comChoiceComparer.com
    CategoriesHow We RankBest Deals

    Top 10 Best refresh eye drops in 2026

    Last Updated - 6/6/2026
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    refresh eye drops
    🏆Best Choice
    1
    Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)
    Refresh

    Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

    9.8
    ChoiceComparer.com Score
    9.8
    / 10
    Outstanding

    Main highlights

    • •IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
    • •MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
    • •CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
    • •GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
    • •PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.
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    View offer on:
    Amazon
    $13.59
    $15.75
    -14%
    Check Price
    2
    Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free,Value Size, 0.01 Fl Oz Single-Use Containers, 70 Count
    Refresh

    Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free,Value Size, 0.01 Fl Oz Single-Use Containers, 70 Count

    9.7
    ChoiceComparer.com Score
    9.7
    / 10
    Outstanding

    Main highlights

    • •Original strength, preservative-free formula
    • •Relieves mild symptoms of eye dryness
    • •Instantly moisturizes and lubricates
    • •Designed to act like your own natural tears
    • •Great for sensitive eyes
    • •Value size. 70 on-the go, single-use vials
    • •Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
    • •The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
    • •Active Ingredient: Carboxymethylcellulose Sodium (CMC) (0.5%); Inactive Ingredients: Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Chloride, and Sodium Lactate. May also Contain Hydrochloric Acid and/or Sodium Hydroxide to Adjust pH.
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    Amazon
    $21.62
    $30.99
    -30%
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    3
    Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
    Refresh

    Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

    9.5
    ChoiceComparer.com Score
    9.5
    / 10
    Outstanding

    Main highlights

    • •FAST-ACTING: Rapid relief to comfort dry, irritated eyes
    • •LASTING RELIEF: Soothes and prevents further irritation
    • •TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
    • •PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
    • •ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
    • •ON-THE-GO VIALS: 30 sterile single-use vials per carton that are easy and safe to use as often as needed
    • •TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
    • •FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
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    Amazon
    $16.08
    $21.99
    -27%
    Check Price
    4
    Refresh Relieva Lubricant Eye Drops, 0.33 Fl Oz Sterile, Packaging may Vary
    Refresh

    Refresh Relieva Lubricant Eye Drops, 0.33 Fl Oz Sterile, Packaging may Vary

    9.4
    ChoiceComparer.com Score
    9.4
    / 10
    Excellent

    Main highlights

    • •Innovative formula relieves discomfort due to dry, irritated eyes
    • •Prevents further irritation
    • •Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
    • •Also available in a preservative-free formula and a formula for contact lens wearers
    • •#1 doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
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    View offer on:
    Amazon
    $14.67
    $19.99
    -27%
    Check Price
    5
    Refresh Celluvisc Lubricant Eye Gel For Dry Eyes, Preservative-Free Drops, 0.01 Fl Oz Single-Use Containers, 30 Count
    Refresh

    Refresh Celluvisc Lubricant Eye Gel For Dry Eyes, Preservative-Free Drops, 0.01 Fl Oz Single-Use Containers, 30 Count

    9.2
    ChoiceComparer.com Score
    9.2
    / 10
    Excellent

    Main highlights

    • •Original strength gel formula
    • •Relieves dry, burning, irritated eyes
    • •Alleviates discomfort
    • •Keeps eyes feeling better longer
    • •#1 doctor recommended with over 30 years of experience.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
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    Amazon
    $15.56
    $22.99
    -32%
    Check Price
    6
    Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count
    Refresh

    Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

    9.1
    ChoiceComparer.com Score
    9.1
    / 10
    Excellent

    Main highlights

    • •Dual-action formula lubricates and hydrates
    • •Relieves mild symptoms of eye dryness
    • •Works fast by delivering soothing moisture
    • •Preservative-free for sensitive eyes
    • •Value size: 60 on-the go, single-use vials
    • •Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
    • •The selling brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
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    View offer on:
    Amazon
    $22.26
    $30.99
    -28%
    Check Price
    7
    Refresh Optive Advanced Eye Drops, 0.33 Fl Oz (Twin Pack)
    Refresh

    Refresh Optive Advanced Eye Drops, 0.33 Fl Oz (Twin Pack)

    8.9
    ChoiceComparer.com Score
    8.9
    / 10
    Great

    Main highlights

    • •Triple-action relief drop
    • •Lubricants and hydrates dry, burning, irritated eyes
    • •Helps prevent tears from evaporating
    • •Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
    • •#1 doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
    Show more
    View offer on:
    Amazon
    $18.11
    $28.99
    -38%
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    8
    Refresh RELIEVA Preservative-Free Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
    Refresh

    Refresh RELIEVA Preservative-Free Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)

    8.8
    ChoiceComparer.com Score
    8.8
    / 10
    Great

    Main highlights

    • •Innovative, preservative-free formula in a multidose bottle
    • •Relieves discomfort due to dry, irritated eyes
    • •Prevents further irritation
    • •Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
    • •Patented multidose bottle with a double locked system keeps drops sterile
    • •Recommended for sensitive eyes
    • •Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
    • •The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
    • •Active ingredients: Carboxymethylcellulose sodium (0.5%) Eye Lubricant, Glycerin (0.9%) Eye Lubricant
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    Amazon
    $14.88
    $22.99
    -35%
    Check Price
    9
    Refresh Digital PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack of 1)
    Refresh

    Refresh Digital PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack of 1)

    8.6
    ChoiceComparer.com Score
    8.6
    / 10
    Good

    Main highlights

    • •Preservative-free formula acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use
    • •Delivers soothing hydration by supporting all three tear film layers
    • •Helps prevent tears from evaporating due to lipid layer deficiencies
    • •Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
    • •30 single-use vials
    • •The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
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    View offer on:
    Amazon
    $11.50
    $21.49
    -46%
    Check Price
    10
    Refresh Tears Lubricant Eye Drops For Dry Eyes, 0.5 Fl Oz Sterile
    Refresh

    Refresh Tears Lubricant Eye Drops For Dry Eyes, 0.5 Fl Oz Sterile

    8.5
    ChoiceComparer.com Score
    8.5
    / 10
    Good

    Main highlights

    • •ORIGINAL STRENGTH: Provides temporary relief for mild, occasional dry eye symptoms
    • •FAST-ACTING: Instantly lubricates and moisturizes
    • •EASY TO USE: Apply 1-2 drops in the affected eye(s) as needed
    • •TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
    • •FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
    Show more
    View offer on:
    Amazon
    $10.68
    $13.99
    -24%
    Check Price
    📊

    📈 How we rank

    With our cutting-edge technology, we examine thousands of products and retailers, assessing reviews, ratings, trends, and sales rankings to identify what matters most to users like you.

    Our team evaluates this data alongside genuine user feedback, merging AI analysis with human insights to provide you with real-time, highly-rated recommendations that empower your decision-making with clarity and confidence.

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    ChoiceComparer.comChoiceComparer.com

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    © 2025 ChoiceComparer.com. All rights reserved.
    Amazon, Amazon Prime, the Amazon logo and Amazon Prime logo are trademarks of Amazon.com, Inc. or its affiliates.
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