Top 10 Best liquid ibuprofen in 2026

Last Updated - 7/1/2026

🏆Best Choice

Motrin

Children's Motrin Oral Suspension, Pain Relief, Ibuprofen, Grape Flavored, 4 Oz

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•Temporarily relieves minor aches & pains due to common cold, flu, sore throat, headache, & toothache
•Temporarily reduces fever
•Contains 100 milligrams of ibuprofen
•Lasts up to 8 hours
•For children ages 2 to 11
•4-ounce bottle

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$7.69

$10.28

-25%

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Tylenol

Tylenol Extra Strength Dissolve Powder Packs, 500 mg Acetaminophen Pain Reliever & Fever Reducer Medicine, Fast Relief for Minor Aches & Pains, Ibuprofen- & Aspirin-Free, On-the-Go Berry Flavor, 32 Ct

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Fast dissolving powder: Tylenol Extra Strength Dissolve Packs deliver 500 mg acetaminophen for pain relief and fever reduction; fast dissolving formula works without water for convenient on-the-go use anytime, anywhere
•Pain relief: Temporarily relieves minor aches and pains from headaches, backaches, minor arthritis, muscle aches, menstrual cramps, toothache, and cold symptoms; safe when used as directed
•On-the-go convenience: Each single-dose packet of this headache medicine dissolves quickly on your tongue with no water needed; perfect for travel, work, or busy lifestyles for fast, portable pain relief
•Great tasting berry flavor: Enjoy a pleasant berry flavor in every packet; designed for adults and children 12 years and older, this pain relief powder is easy to use and provides effective symptom relief
•Extra strength formula: From the #1 doctor recommended brand for pain relief and fever reduction, experience extra strength pain relief in a portable, easy-to-carry format

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$11.77

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A+Health

A+Health Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), 300 Count

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENT IBUPROFEN 200MG: Contains active ingredient Ibuprofen 200mg (nonsteroidal anti-inflammatory drug)—compare to the active ingredient in Advil Liquid-Gels
•TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor aches and pains due to headache, toothache, backache, menstrual cramps, the common cold, muscular aches, and minor pain of arthritis
•SOFTGELS: Each bottle contains 300 softgels, which are liquid-filled capsules
•GREAT VALUE: Provides temporary relief from most common aches and pains at a great value
•DON'T LET PAIN GET IN YOUR WAY: Whether you have minor arthritis pain or other aches or pains, you can find relief with A+ Health Ibuprofen 200mg Softgels

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$14.69

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Advil

Advil Liqui-Gels Minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 80 Liquid Filled Capsules

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•One bottle of 80 Advil Liqui-Gels minis Pain Reliever and Fever Reducer Liquid Filled Capsules, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief
•Mini ibuprofen liqui-gels are easy to swallow
•Headache medicine, back pain medicine and joint or minor arthritis pain reliever that are faster and stronger on tough pain than Tylenol Rapid Release Gels.
•Pain reliever and fever reducer for adults designed for fast absorption, with the same strength as regular size Advil Liqui-Gels
•Fever medicine and headache pain relief, period pain relief, joint pain medicine and back pain medication for adults and children 12 years and older
•Take these Advil mini Liqui-Gels as directed - the perfect addition to your college dorm room essentials
•HSA and FSA eligible product

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$9.97

$11.49

-13%

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Vicks

Vicks PainQuil & PainQuil PM Pain Relief Liquid, 1000mg Acetaminophen, 2x12 oz

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•MAX STRENGTH PAIN RELIEVERS: Use PainQuil for max strength pain relief (1000mg Acetaminophen) for pain relief anytime. At night, use PainQuil PM for max strength nighttime pain relief, with 1000mg Acetaminophen and 50mg DPH per dose.
•STARTS WORKING FAST: PainQuil & PainQuil PM start working fast for relief of headaches, sore throat, minor aches & pains. PainQuil PM relieves sleeplessness + headaches, sore throat, minor aches & pains, so sleep soundly.
•LIQUID PAIN RELIEF: PainQuil and PainQuil PM offer max strength pain relief in a soothing liquid.
•GREAT TASTE: These adult pain relief liquids are deliciously flavored; PainQuil is black cherry flavored, and PainQuil PM is midnight cherry flavored.
•NON-HABIT FORMING: both PainQuil and PainQuil PM are non-habit forming. They are also free of sugar and free of high fructose corn syrup.
•FROM THE MAKERS OF VICKS: All PainQuil products are specifically formulated by our team of dedicated scientists, with over 125 years of health care expertise.

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$14.97

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Amazon Basic Care

Amazon Basic Care Ibuprofen Liquid Gels 200 mg, Pain Reliever/Fever Reducer Liquid Filled Capsules, For Headache, Toothache, Backache, Menstrual Cramps and More, 160 Count

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•ACTIVE INGREDIENT: Amazon Basic Care Ibuprofen Liquid Gels (liquid filled capsules) contain solubilized Ibuprofen equal to 200 mg Ibuprofen (NSAID),* pain reliever/fever reducer (present as the free acid and potassium salt). *nonsteroidal anti-inflammatory drug. Compare to Advil Liqui-Gels active ingredient
•WHAT CAN IBUPROFEN LIQUID GELS DO? Temporarily relieves minor aches and pain from headache, toothache, backache, menstrual cramps, the common cold, muscular aches, minor pain of arthritis, and temporarily reduces fever
•PAIN OR FEVER associated minor pain of arthritis, backache, headache or the common cold can interfere with daily activities. Amazon Basic Care Ibuprofen Liquid Gels temporarily relieves minor pain and fever to help you get back on track.
•TAKE CARE OF YOURSELF: Do not put up with headache, backache, minor arthritis pain, or even the minor aches and pains of the common cold. Amazon Basic Care Ibuprofen Liquid Gels 200 mg is a pain reliever and fever reducer -- plus, it is gluten free.
•IBUPROFEN LIQUID GELS contain Solubilized Ibuprofen equal to Ibuprofen 200 (*NSAID) (present as the free acid and potassium salt). (*nonsteroidal anti-inflammatory drug).

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$10.94

$12.00

-9%

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P Puregen Labs

Puregen Labs Adult Extra Strength Acetaminophen Liquid 500mg/15ml - 8 fl oz Rapid Burst Pain Reliever/Fever Reducer, Cherry Flavor | Muscle & Joint Pain Relief | Arthritis Pain Relief

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•✅PAIN RELIEVER & FEVER REDUCER: This liquid medication contains acetaminophen, which is commonly used to relieve pain and reduce fever temporarily while offering relief from minor headache, muscles and body aches. Also helps with pains associated with arthritis.
•✅EXTRA STRENGTH: This formulation is extra strength, providing a higher dose of acetaminophen per milliliter compared to regular strength products.
•✅RAPID BURST CHERRY FLAVOR: - This easy to take liquid comes in a cherry flavor everyone will love. Made in United States.
•✅NO ASPRIN: Each dose contains 500 mg of pain relieving, fever reducing acetaminophen without any aspirin. This aspirin-free arthritis pain relief, back pain relief, joint pain relief, and muscle pain relief medicine is formulated in cherry flavor liquid.
•✅WARNING: It's important to follow the dosing instructions carefully, as too much acetaminophen can be harmful. Always use the provided measuring device to ensure accurate dosing.

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$9.95

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MAJOR

MAJOR Adult Extra Strength Liquid Acetaminophen 500mg - Helps Relieve Pain and Reduce Fevers - Aspirin Free - Cherry Flavor - 8 Fl Oz (2 Pack)

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•EXTRA-STRENGTH ACETAMINOPHEN LIQUID: Major acetaminophen helps temporarily reduce fevers and relieve minor aches and pains due to headaches, toothaches, muscular aches, the common cold, backache, minor pain from arthritis, and cramps.
•INGREDIENT: Each 15mL dose contains 500mg of acetaminophen, an ingredient that helps relieve pain and reduce fevers.
•HOW TO USE: Adults and children 12 years and over: take 15 to 30mL every 4 to 6 hours as needed. Do not take more than 90mL in 24 hours, unless directed by a doctor. Children under 12 years: do not use.
•QUALITY FORMULATION: We maintain high standards of care through strict regulatory compliance to deliver carefully formulated pain relief liquid.
•MAJOR PHARMACEUTICALS: At Major Pharmaceuticals, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering quality OTC and vitamin supplements.

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$17.48

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MAJOR

MAJOR Adult Extra Strength Liquid Acetaminophen 500mg - Helps Relieve Pain and Reduce Fevers - Aspirin Free - Cherry Flavor - 8 Fl Oz (1 Pack)

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•EXTRA-STRENGTH ACETAMINOPHEN LIQUID: Major acetaminophen helps temporarily reduce fevers and relieve minor aches and pains due to headaches, toothaches, muscular aches, the common cold, backache, minor pain from arthritis, and cramps.
•INGREDIENT: Each 15mL dose contains 500mg of acetaminophen, an ingredient that helps relieve pain and reduce fevers.
•HOW TO USE: Adults and children 12 years and over: take 15 to 30mL every 4 to 6 hours as needed. Do not take more than 90mL in 24 hours, unless directed by a doctor. Children under 12 years: do not use.
•QUALITY FORMULATION: We maintain high standards of care through strict regulatory compliance to deliver carefully formulated pain relief liquid.
•MAJOR PHARMACEUTICALS: At Major Pharmaceuticals, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering quality OTC and vitamin supplements.

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$8.85

$9.99

-11%

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Children's Advil

Children's Advil Pain Reliever and Fever Reducer, Dye Free and Sugar Free Ibuprofen Oral Suspension, Berry Flavored - 4 Fl Oz

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•One 4 fluid ounce bottle of Children's Advil Pain Reliever and Fever Reducer, Dye Free and Sugar Free Ibuprofen Oral Suspension, Berry flavored
•Liquid medicine with a pleasant berry flavor
•Children's pain reliever that relieves minor aches and pains due to common cold or teething
•Sugar free and dye free formulation that won't stain washables
•Fever and pain relievers for ages 2 to 11 years- Great to have on hand for back to school
•Give appropriate weight-based dose every 6 to 8 hours as needed for symptoms
•HSA and FSA eligible products

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$7.35

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