Top 10 Best itch cream in 2026

Last Updated - 6/18/2026

🏆Best Choice

Lotrimin

Lotrimin Ultra Jock Itch Cream - Powerful Butenafine Hydrochloride Treatment for Jock Itch, 0.42 Ounce (12 Grams) (Packaging May Vary)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•Provides Soothing Itchy Skin Relief: Treat the discomfort of itchy skin on the groin and inner thighs with Lotrimin ultra-jock itch cream
•Proven to cure most jock itch: Clinically proven to cure most jock itch infections, Lotrimin Ultra Antifungal Cream kills the fungus that causes tinea cruris, commonly known as jock itch
•Formula: Lotrimin Ultra fungus cream contains butenafine hydrochloride to help kill the fungus that cause jock itch in your groin area. Store between 20° to 25°C (68° to 77°F)
•Safe For Kids Over 12: Help your teenage athlete with the burning, chafing skin caused by jock itch on his or her inner thighs and crotch with this anti fungal cream
•Ideal For Men and Women: Many people assume that only men get jock itch, but women are also prone to fungal infections on their crotch skin

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$12.47

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Vagisil

Vagisil Regular Strength Anti-Itch Feminine Cream for Women, Gynecologist Tested, Hypoallergenic, Fast-acting and Long-lasting Itch Relief, Vaginal Moisturizer Soothes and Cools, 1 oz (Pack of 1)

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Vagisil Anti-itch Feminine Cream moisturizes while relieving even the most painful, burning itch fast in the vaginal area. Provides lasting relief.
•Specially designed for the vaginal area to relieve everyday itch and itch associated with yeast infections. Fast-acting and non-steroidal.
•Skin-soothing formula infused with Vitamins A, D, E, and Aloe to soothe and cool.
•Non-irritating, hypoallergenic formula. Gynecologist tested and non-greasy.
•The only vaginal itch cream with LactoPrebiotic. Great for intimate skin and reducing further irritation.

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$5.79

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Aidance

Femmesil Feminine Care Vaginal Health Antifungal Cream for Relief from Yeast Infection, Itch & Irritation, Vaginal Cream for Women, 1.7oz Tube

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•SOOTHING RELIEF: Experience soothing relief for vaginal irritation with Femmesil Feminine Ultra Therapy Vaginal Health Antifungal Cream, a potent ally against yeast infections. As a vaginal itch cream, it serves as a gentle companion for your sensitive skin, devoid of parabens, alcohol, and dyes that could potentially cause further irritation.
•POWERFUL ANTIFUNGAL CREAM: Our antifungal vaginal cream contains 1% Clotrimazole and is specifically designed to alleviate the symptoms triggered by yeast infections. This vaginal cream synergizes natural ingredients to soothe irritation and restore balance, making it safe for daily use.
•HIGH QUALITY NATURAL INGREDIENTS: Our natural vaginitis treatment is a powerful blend of organic ingredients like shea butter, cottonseed oil, and jojoba oil. This natural yeast infection treatment for women offers a gentle cleanse without resorting to harsh chemicals, adopting a natural approach to feminine care that respects both your body and the environment.
•MADE IN THE USA: Trust in the quality of Femmesil feminine care products, crafted with pure and natural ingredients. These feminine products are made in the USA and adhere to the highest standards of quality and safety, valuing your health and wellbeing. FSA/HSA eligible.

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$23.95

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PHARMBANNER

Antifungal Cream for Jock Itch, Ringworm, Psoriasis & Athlete’s Foot – Extra Strength Relief for Itchy, Burning Skin – Fast-Acting Formula for Tinea Cruris, Tinea Versicolor & Skin Irritations

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•✅ Fast, Targeted Relief for Itchy, Irritated Skin – Formulated with 1% Clotrimazole, this extra strength antifungal cream helps relieve itching, burning, scaling, and redness caused by jock itch, athlete’s foot, ringworm, and psoriasis.
•✅ Plant-Based Soothing Formula – Enriched with Tea Tree Oil, Aloe Vera, Prunella, and Witch Hazel, this cream helps calm inflamed skin and supports natural recovery without harsh chemicals.
•✅ Hydrating & Non-Greasy Texture – Designed for daily use, this cream absorbs quickly and leaves no greasy residue. Ideal for use on feet, groin, hands, or other affected areas.
•✅ Protects and Restores Skin Barrier – In addition to fighting fungal infections, it helps repair cracked, dry skin and prevents further irritation with nourishing botanicals and moisturizers.
•✅ Safe for All Skin Types – Dermatologist-reviewed ingredients make it suitable for both men and women. Use consistently twice daily for 2–4 weeks for best results. Manufactured in a GMP-compliant facility.
•✅ Trusted & Satisfaction Guaranteed – We stand behind our product with exceptional customer support. If you're not 100% satisfied, reach out to us, and we’ll make it right—your healthy skin is our top priority!

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$21.99

$24.99

-12%

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BeeFriendly

BeeFriendly Organic Vaginal Moisturizer, USDA Certified, Natural Vulva Cream For Dryness, Itching, Irritation, Redness, Chafing Of Vagina Due To Menopause & Thinning 2 oz

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Rejuvenate dry thinning vulvar tissue - All Natural & Organic vaginal cream helps rejuvenate and rehydrate vaginal dryness due to menopause, breastfeeding or other conditions. This feminine moisturizers organic ingredients help reduce irritation, itchiness, redness and burning of your most intimate areas
•Non Sticky - Smooth and oil based, this feminine moisturizer is formulated with your safety in mind as to not cause yeast infections or UTI's from use. Long lasting. Not latex compatible. Non GMO. Fragrance free.
•100% All Natural & Certified Organic Ingredients Handmade in USA. Purified Water, Organic Extra Virgin Olive Oil, Beeswax with Pollen & Propolis, Vitamin E. No chemicals or fillers, no animal testing, no fragrances, no estrogen, no steroids, no dyes, no hormones, no synthetic preservatives, no petroleum, no parabens. Every ingredient is formulated to help restore your sensitive skin to its supple, youthful feminine best.
•USDA Certified Organic - Beeswax improves the elasticity, softness and suppleness of your skin. Propolis (contained within the Beeswax) helps the skin to heal & protects it from further damage. Bee pollen (contained within the Beeswax) is rich in many nutrients. Organic extra virgin olive oil has vitamin A & vitamin E & same fatty acids as your skin
•Formulated to deeply moisturize. No fillers or binders, so the vaginal cream is very concentrated. A little goes a long way towards menopause relief! Every ingredient has a beneficial effect on the skin. Leaves your skin well nourished & feeling hydrated & healthy. Fight off the free radicals. BeeFriendly makes the highest quality skin care products around!

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$28.99

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NeilMed

NeilMed Hydrocortisone 1% Anti Itch Cream with Aloe Vera. 2oz – Fast Relief Soothing and Calming - Ideal for Itching, Rashes, Redness, Inflamation & Other Skin Irritations

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•1% USP HYDEROCORTISON CREAM WITH ALOE - Maximum strength 1% hydrocortisone cream provides fast relief from itches associated with minor skin irritations, dry skin, redness, flare ups, rashes, mosquito and insect bites.
•SOOTHING & CALMING EFFECT - Extra strength when you need it the most. NeilMed Hydrocortisone cream with Aloe is safe and gentle to use even on dry skin. Fast relief from irritation, rashes and itchy bites.
•SAFE - NeilMed Hydrocortisone Cream 1% with ALoe is fragrance free and is hypoallergenic. Apply to affected area not more than 3 to 4 times daily.
•For adults and children 2 years of age or older. For external use only. When using this product avoid contact with the eyes.
•CONTAINS - One 2oz tube of NeilMed Hydrocortisone Cream 1% with Aloe

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$3.50

$6.99

-50%

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berkley jensen

Berkley Jensen Maximum Strength Anti-Itch Cream (4 oz.), with Calming Aloe Vera, 1% Hydrocortisone Itch Relief for Eczema, Psoriasis, Bug Bites, Poison Ivy, Oak and Sumac, 2 oz. Tube (Pack of 2)

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•SOOTHING RELIEF - Our anti itch cream may help address discomfort caused by minor skin itching, irritation, redness, bites, rashes, cosmetics, detergents, soaps, jewelry, sumac, oak, or eczema.
•LONG-LASTING EFFECTS - When applied to the affected area, our topical itchy skin relief cream can provide quick and reliable relief from minor itching and irritation that lasts up to ten hours.
•EASY TO APPLY - Clean your hands before applying a thin layer of the hydrocortisone ointment 1 percent cream onto the affected area. Apply the ointment 2-3 times per day or as advised by your doctor.
•SUPERB VALUE - Each pack contains two 2oz. tubes of our hydrocortisone cream 1%. Keep a tube at home for emergencies and have another one handy in your bag or purse while you're out and about.
•MEETS QUALITY STANDARDS - Just like all our wellness products, our hydrocortisone 1% cream is manufactured in a modern facility that complies with stringent industry quality and safety protocols.

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$8.72

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TAGRID

TAGRID Jock Itch Cream, Jock Itch, Jock Itch Cream Extra Strength for Men & Women, Itchy Balls Cream, Yeast Infection Treatment for Men & Women, Itch Cream - Powerful and Fast - 60g

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•With our Unique Formula: You don't have to wait days or weeks to see the first results. Your tinea cruris symptoms will disappear within a few hours and be relieved within 24 hours. You will see the results you have been eagerly anticipating within a week.
•Fast and Effective: It Soothes the affected area with a cooling sensation. This fast-acting formula provides quick relief and starts working immediately. ( Tip: If your skin is scratched, there may be some slight discomfort, but believe that after 5 minutes, you will be pleasantly surprised by the comfort our product brings.)
•Does Not Stain Clothes: Our Jock Itch cream is non-staining, skin that absorbs quickly ointment that's easy to apply.
•Convenient for Daily Use: comes in hygienic and convenient packaging for easy storage and travel.
•Suitable for Most Skin Types: Our products not only have good feedback from men, but also from women. And it can be used on most skin types.

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$24.99

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TAGRID

Jock Itch Antifungal Cream for Skin: 7X Fast Extra Strength Treatment Cream - Premium Anti-Fungal Relief for Men and Women, Soothes Itching & Burning, Clinically Proven, 3.53 OZ

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•With our Unique Formula: You don't have to wait days or weeks to see the first results. Your tinea cruris helps reduce symptoms within a few hours and be may help within 24 hours. You will see the results you have been eagerly anticipating within a week. *Helps maintain results without rebound – consistent use for 3-4 weeks recommended.
•Fast and Effective: It Soothes the affected area with a cooling sensation. This fast-acting formula provides quick relief and starts working immediately. ( Tip: If your skin is scratched, there may be some slight discomfort, but believe that after 5 minutes, you will be pleasantly surprised by the comfort our product brings.)
•Does Not Stain Clothes & Convenient for Daily Use: : Our Jock Itch cream is non-staining, skin that absorbs quickly ointment that's easy to apply. Comes in hygienic and convenient packaging for easy storage and travel.
•Suitable for Most Skin Types: Our products not only have good feedback from men, but also from women. And it can be used on most skin types.
•NDC: 85384-0003-1

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$27.97

$29.99

-7%

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Generic

1pk Maximum Strength Feminine Anti Itch Cream Hydrocortisone Sensitive Women 1oz 0.5% Hydrocortisone Cream Itch Relief Fast Feminine Care Moisturizer Itch Relief Feminine Hygiene Products for Women

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•1 Pack Maximum Strength Anti Itch Feminine Care sensitive hydrocortisone formula 1oz. Itch Stopping Cream
•Relieves Itching & Irritation: Provides fast relief from itching and discomfort in the intimate area.
•Gentle & Non-Irritating: Formulated without harsh chemicals or fragrances, suitable for sensitive skin.
•Compact & Travel-Friendly: Convenient 1 oz size, perfect for on-the-go use or travel.

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$8.49

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