Top 10 Best pain relief in 2026

Last Updated - 6/25/2026

🏆Best Choice

Dermoplast

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•Relieve pain fast: Childhood and family life are full of little irritations. Use Dermoplast pain and itch spray to quickly relieve the pain and itch of minor cuts, scrapes, burns, insect bites, and sunburn
•Soothe, cool, and moisturize: Dermoplast combines hospital strength Benzocaine with Aloe, lanolin and Menthol to soothe and moisturize skin affected by insect bites and stings or minor cuts, scrapes, and burns
•Must have for moms: Many new moms first use Dermoplast Spray in the hospital. The no-touch application and quick pain relief also make it ideal for kids 2 and up. Works on sensitive and hard to reach areas
•Soothing relief: With Dermoplast maximum strength formulas, you can bring hospital-strength comfort home to help relieve pain from minor cuts, scrapes, burns, insect bites and other skin irritations
•Comfort and care: Hospitals trust Dermoplast for post-partum pain relief and comfort. Use our first aid and pain relieving sprays at home to provide safe, effective pain and itch relief for your whole family

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$7.74

$8.99

-14%

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Bactine MAX

Bactine Max Pain Relieving Antiseptic Spray with Lidocaine, First Aid Pain + Itch Relief, No-Sting, Kills 99% of Germs*, 5oz

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Bactine Max Pain Relieving Antiseptic Spray with Lidocaine, First Aid Pain + Itch Relief, No-Sting, Kills 99% of Germs*, 5oz
•Pain Relief + Skin Infection Protection --- Get a better value than tiny tubes of ointment. Bactine Max Pain Relieving Spray is an antiseptic minor wound, burn, and bug bite cleanser that provides immediate pain relief + itch relief. All while protecting against infection.
•Kills 99% of Germs --- Feel confident knowing you are protected. Bactine Max uses benzalkonium chloride and effectively kills 99% of germs associated with skin infections. It stops the growth of bacterial microorganisms on the skin to prevent infection of wounds, burns, and insect bites.
•Max Strength Pain Relief --- Boo-boos hurt enough. Why add to that? Formulated with 4% Lidocaine, a topical analgesic, that numbs the pain. It interferes with the transmission of nerve pain signals from the site of application. It has the maximum lidocaine amount allowed by the FDA for OTC products for local anesthetics.
•No-Sting Means No Worries --- Treat your family with a tear free first aid wound care. Unlike other hydrogen peroxide or alcohol based wound care products, Bactine cleanses and protects without a painful, harsh sting. It provides temporary relief of pain and itching from minor wounds, bug bites, and burns. It won't leave a brown stain on skin like iodine-based products.
•Safe and Highly Trusted --- Around since 1947, Bactine Max Spray is safe for adults and children 2 years old plus. To use just clean the affected area; spray a small amount on the area 1-3 times daily; may be covered with a sterile bandage (let dry first).

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$5.74

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Alocane

Alocane Max Emergency Burn Gel, 4% Lidocaine Hydrochloride, .13% Benzalkonium Chloride, Maximum Strength Relief, Itch Relief, For Sunburns, Kitchen, Radiation, Chemical, First-Degree Burns, 4 Fl Oz

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•LIDOCAINE MAXIMUM STRENGTH: Features 4% Lidocain Hydrochloride and .13% Benzalkonium Choride gel for effective itch relief, sunburn relief, and minor burns
•EFFECTIVE BURN TREATMENT: This formula combines pain cream gel and burn cream gel for quick relief, absorbing fast into the layers of skin to support healing of burns
•SOOTHING INGREDIENTS: Infused with aloe vera leaf juice and designed as sunburn treatment, it alleviates discomfort from burns that come from sun exposure, flames, electricity, as well as bug bite itch
•RECOMMENDED BY PHYSICIANS AND PHARMACISTS: This lidocaine cream is suitable to use on first degree burns by healthcare professionals
•EASY TO USE: Add this burn ointment gel to your first aid kits for vehicles to have mess-free burn relief on-the-go; simply apply generously to the affected area up to four times daily for best results

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$11.89

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EBANEL LABORATORIES

Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb spray enhanced with 0.25% Phenylephrine HCl and Allantoin, temporarily relieves pain, burning, itching, and discomfort, reduces swelling, inflammation, soreness, and protects irritated skin in local and anorectal areas
•5% Lidocaine Spray Maximum Strength - This pain relief anti itch spray provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
•Enhanced Liposomal Deep Penetrating Pain Relief Spray - Best efficacy, fast-acting & long-lasting. It begins numbing in 2-3 minutes, peaks after 5-10 minutes, and lasts for 1 hour from its peak. Numbing performance may vary depending on the thickness of skin area, and individual metabolism
•Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply during and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy, hands-free application. No need to remove it after
•Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

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$19.99

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Dermoplast

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz, Pack of 2 (Packaging May Vary)

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Pack of 2 Dermoplast Pain, Burn, Itch Relief Spray
•Relieve pain fast: Childhood and family life are full of little irritations. Use Dermoplast pain and itch spray to quickly relieve the pain and itch of minor cuts, scrapes, burns, insect bites, and sunburn
•Soothe, cool, and moisturize: Dermoplast combines hospital strength Benzocaine with Aloe, lanolin and Menthol to soothe and moisturize skin affected by insect bites and stings or minor cuts, scrapes, and burns
•Must have for moms: Many new moms first use Dermoplast Spray in the hospital. The no-touch application and quick pain relief also make it ideal for kids 2 and up. Works on sensitive and hard to reach areas
•Comfort and care: Hospitals trust Dermoplast for post-partum pain relief and comfort. Use our first aid and pain relieving sprays at home to provide safe, effective pain and itch relief for your whole family

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$18.78

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Solarcaine

Solarcaine Aloe Sunburn Relief Spray with 4% Lidocaine - After Sun Care Relief for Burns, Scrapes & Itch - Aloe Spray to Soothe, Cool & Replenish Skin - 4oz

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•IMMEDIATE BURN RELIEF: Soothe your burns in a flash with Solarcaine. Our medicated burn relief aloe spray is specially formulated with Lidocaine HCL to deliver fast, cooling pain relief for sunburns, minor burns, cuts, scrapes and insect bites. An after sun care essential
•COOLING, ONE TOUCH SPRAY: Soothe sensitive burns without rubbing irritated skin. Simply spray Solarcaine with our easy 360 degree sprayer and allow the medicated burn relief go to work
•ALOE VERA + LIDOCAINE: Our gentle pain relief spray is infused with Aloe Vera, lidocaine and Vitamin E to instantly cool, soothe and relieve your burns & bites. Leaves no sticky residue
•MOISTURIZING & SKIN SAFE: Helps reduce skin irritation & promote healing from sunburn by reducing dryness & keeping skin moisturized. A fragrance Free, alcohol free, non-stinging alternative. Dermatologist tested. #1 Pharmacist Recommended
•HOW TO USE: Shake well. Adults and children 2 years of age and older: Apply to affected area not more than 3 to 4 times daily. To apply to face, spray in palm of hand and gently apply. Children under 2 years of age: do not use, ask a doctor

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$9.97

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MG217

MG217 Maximum Strength Pain Relief Cooling Burn Spray, with Lidocaine and Aloe Vera, 4 oz

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•One 4 oz can of MG217 Maximum Strength Pain Relief Cooling Burn Spray
•Sunburn spray with 4% Lidocaine, aloe vera and camphor for quick, maximum strength relief with a cooling, moisturizing formula
•Topical pain reliever and itch soother works on minor cuts, scrapes, burns, sunburns, insect bites, stings and skin irritations
•First aid antiseptic can help to promote healing of minor cuts and scrapes by keeping the area clean and protected
•Non-aerosol can sprays in all directions for easy use

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$9.76

$10.99

-11%

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Globe

Globe (3 Pack) Burn Spray, Lidocaine 2%. Topical Anesthetic Pain Relief and Numbing 2 oz Spray Bottle

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•FAST & EFFECTIVE: First aid to help prevent risk of infection from minor scalds, scrapes and burns.
•FIRST AID KIT: Globe Burn Spray, Lidocaine 2%. Topical Anesthetic Pain Relief and Numbing 2 oz Spray Bottle is a must have product in your first aid kit. Its a skin care treatment for minor Scalds, Burns and Sunburns. Frist class First Aid Treatment for minor Scalds, Burns and Sunburns.
•EASY TO TAKE WITH YOU: Keep Globe Burn Spray, Lidocaine 2% Spray in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carryon luggage. The convenience of the 2 oz spray bottle size can go with you anywhere.
•WHATS INSIDE: This product is made with Lidocaine 2% and purified water. Simply clean the affected area and use the convenient pump spray to apply a small amount one to three times daily. Each Pump Spray Bottle Contains 2-ounces. (3 Pack)
•QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. Trifecta Pharmaceuticals USA, who manufacturers the Globe Brand and is based in sunny Fort Lauderdale, Florida.

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$9.99

$12.99

-23%

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Alocane

ALOCANE Emergency Burn Spray, 4% Lidocaine Max Strength Fast Pain Itch Relief for Minor Burns, Sunburn, Kitchen First Aid Treatment Burn Care, 4 Fl Oz

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Alocane burn gel is a water based formula with an efficient proprietary transfer vehicle that quickly absorbs deep into the layers of skin. Soothing Aloe Gel and Vitamin E, assists the healing process
•With the 4% Lidocaine, which is the maximum percentage of Lidocaine allowed by the US FDA for over the counter products, It relieves pain fast while soothes the skin
•Rmmended by physicians and pharmacists to use on first Degree burns and including: sunburn, kitchen burns, electricity burns, heat, light, itches, rashes, bug bites, and much more
•Easy to apply generously to the burned area Up to 4 times daily, treat any burn even 1st Degree burns, clear Gel, immediate burn, little to no smell, rmmended for children and adults
•The Brazilian Aloe Gel has a cooling effect on the itchy hot skin and promotes healing while the Lidocaine decreases healing time while Stopping the burning fast. A must have for your first aid kit

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$12.99

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Globe

Globe Burn Spray, Lidocaine 2%. Topical Anesthetic Pain Relief and Numbing 2 oz Spray Bottle

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•FAST & EFFECTIVE: First aid to help prevent risk of infection from minor scalds, scrapes and burns.
•FIRST AID KIT: Globe Burn Spray, Lidocaine 2%. Topical Anesthetic Pain Relief and Numbing 2 oz Spray Bottle is a must have product in your first aid kit. Its a skin care treatment for minor Scalds, Burns and Sunburns. Frist class First Aid Treatment for minor Scalds, Burns and Sunburns.
•EASY TO TAKE WITH YOU: Keep Globe Burn Spray, Lidocaine 2% Spray in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carryon luggage. The convenience of the 2 oz spray bottle size can go with you anywhere.
•WHATS INSIDE: This product is made with Lidocaine 2% and purified water. Simply clean the affected area and use the convenient pump spray to apply a small amount one to three times daily. Each Pump Spray Bottle Contains 2-ounces.
•QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. Trifecta Pharmaceuticals USA, who manufacturers the Globe Brand and is based in sunny Fort Lauderdale, Florida.

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$4.99

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