Top 10 Best pain relief cream in 2026

Last Updated - 6/28/2026

🏆Best Choice

Boiron

Boiron Arnicare Gel for Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•ARNICA FOR PAIN: This homeopathic medicine helps temporarily relieve muscle pain & stiffness due to minor injuries, overexertion & falls. Also great for pain, swelling, & discoloration from bruises.
•TOPICAL PAIN RELIEF: Our non-greasy, water-based formula absorbs quickly & is unscented & paraben-free. This cooling gel is great for relief following an injury, intense workout, or general overexertion.
•PLANT-BASED ACTIVE INGREDIENT: The Arnica montana plant is a natural pain reliever. This popular homeopathic medicine temporarily relieves muscle pain & stiffness without unwanted drowsiness. Fluoride-Free
•HOMEOPATHIC MEDICINE uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our tablets, pellets, & topical treatments work with your body without the risk of contraindications, or known drug interactions.
•THE BOIRON PROMISE: We believe there’s more than one way to feel better. Since 1932, we have been committed to providing quality medicines. As a world leader in homeopathy, our passion is your health. Our promise is your satisfaction.

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$8.32

$12.59

-34%

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Bengay

Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•4-ounce tube of non-greasy Bengay Ultra Strength Topical Pain Relief Cream with three powerful ingredients to ease backaches, minor arthritis, muscle, and joint pain
•Topical analgesic cream provides relief from muscle aches and joint pain. It contains three pain-relieving ingredients for powerful relief at the site of pain: 4% camphor, 10% menthol, and 30% methyl salicylate
•Pain relief cream provides temporary relief from minor aches and pains of muscles and joints associated with simple backaches, minor arthritis pains, strains, bruises, and muscle sprains
•Bengay, a physician-recommended OTC topical analgesic brand, contains more pain-relieving ingredients than any other Bengay product. Adults and children 12 years and older, apply to the affected area no more than three to four times daily
•Pack the topical pain relief analgesic in a convenient tube in your gym bag or suitcase for port-able & on-the-go relief from aches, minor arthritis, joint, and back pain

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$5.18

$6.97

-26%

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Aspercreme

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Contains one (1) 4.3-oz. tube of Aspercreme Pain Relief Cream With Max-Strength Lidocaine and Moisturizing Aloe
•Fast-Acting Relief: Experience rapid and lasting pain relief with max-strength 4% lidocaine topical numbing cream, designed to target nerves and numb away pain
•Non-greasy Formula: Fragrance-free Aspercreme moisturizes and relieves without greasy residue or strong odor
•Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
•Travel-Size: Take your pain relief solution on the go in a compact and portable tube
•Aspercreme is the topical lidocaine brand in the U.S.

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$7.48

$11.49

-35%

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Biofreeze

Biofreeze Pain Relief Cream for Knee, Neck, Hip, Joint, Shoulder, & Simple Backache, Arthritis Pain Reliever, Sore Muscle Relief, Cooling Menthol Pain Cream, 3 Oz

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•PAIN RELIEVER: Enjoy cooling pain relief with Biofreeze, the #1 clinician recommended menthol topical pain relief brand*; Helps relieve minor aches & pains of muscles & joints associated with simple backache, arthritis, strains, bruises & sprains
•LOWER BACK PAIN RELIEF: Ideal for both athletes & everyday ache sufferers, our non-greasy pain relief cream provides targeted menthol pain relief for simple backache; Also helps relieve soreness during muscle recovery
•NECK PAIN RELIEF: Relieve neck pain with Biofreeze; Trusted by chiropractors, podiatrists, physical therapists, massage therapists, retail pharmacists, & athletic trainers
•FAST-ACTING BIOFREEZE CREAM WITH NATURAL MOISTURIZERS: When you're in pain, you need a fast-acting formula that works - Biofreeze delivers cooling, targeted relief and won't wear off quickly, so you can get back to your best
•SHOULDER PAIN RELIEF: Whether you have pain from a bruise, arthritis, or an intense workout, our moisturizing pain relief cream powered by menthol stimulates cold receptors that create a cooling sensation, helping to relieve pain
•TRAVEL SIZE PAIN CREAM: Don't let pain interrupt your vacation - Biofreeze 3 oz cream jar is TSA-friendly and perfect for on-the-go pain relief, so you can focus on your adventure
•FSA/HSA STORE ELIGIBLE ITEMS: Biofreeze products are FSA/HSA eligible which means you could save up to 30% (Product eligibility may vary by plan; Check with your benefits administrator to determine which expenses are eligible before you shop)
•QUALITY TOPICAL PAIN RELIEF: Product is free of NSAIDs, Ibuprofen, Aspirin, and Salicylate, and is not tested on animals; Biofreeze provides effective, cooling pain relief trusted by healthcare professionals
•Based on an Ipsos Clinician Survey of: chiropractors, podiatrists, physical therapists, massage therapists, retail pharmacists, & athletic trainers, of OTC topical pain relief products; among clinicians who recommend brands containing menthol

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$13.18

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HealthWise

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
•FAST-ACTING LIDOCAINE — Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
•NON-GREASY FORMULA — Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
•SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
•Compare to Aspercreme with Lidocaine active ingredients
•2.7 oz. bottle (49.6g)

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$3.99

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Icy Hot

Icy Hot Original Pain Relief Cream, 3 oz., Feel It Working Instantly

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•Includes one (1) 3-oz. tube of Icy Hot Original Pain Relief Cream
•This pain cream provides relief for minor pains associated with arthritis, back aches, body aches, leg cramps and sore muscles
•Icy Hot Extra Strength Pain Cream starts working on contact to bring fast relief that lasts for hours
•Rub in this non-greasy topical pain cream for quick relief when you need it most
•Icy Hot is the number-one topical pain relief brand* *among OTC topical analgesics

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$7.98

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HealthWise

HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
•PAIN RELIEVING LIDOCAINE + BENZYL ALCOHOL — Powerful pain relief ingredients: 4% lidocaine plus 10% benzyl alcohol work together by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
•NON-GREASY FORMULA — Non-greasy formula goes on smooth; safely apply 3-4 times daily
•30-APPLICATIONS PER TUBE — Only a dime size of cream is needed per application to targeted areas for up to 30 applications in each tube
•SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
•Compare to Salonpas Lidocaine Plus Pain Relieving Cream active ingredients
•3.0 oz. tube (85g)
•Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
•Always read detailed instructions before use

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$3.99

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Hempvana

Hempvana 5% Lidocaine Relief Cream, Maximum Strength, AS-SEEN-ON-TV, Strong Cream, Numbs Irritated Nerves for Fast Anorectal Relief, Non-Greasy, Targeted Long-Lasting Relief. Enriched with Hemp, 3 Oz

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•HEMP SEED OIL: our 5% Maximum Strength pain relief cream is enriched with ultra-moisturizing Hemp Seed Oil
•MAXIMUM STRENGTH: strongest lidocaine to give you maximum relief from inflammation and swelling
•LIDOCAINE FORMULA: We blend 100% pure cold-pressed hemp seed oil with FDA-listed 5% Lidocaine for powerful pain relief
•TARGET THE PAIN: our Maximum Strength Relief Cream targets pain right where it hurts. Soothes aggravated anorectal nerves
•NON-GREASY: Unlike other creams that leave a greasy mess, Hempvana is non-greasy and absorbs quickly
•ODOR FREE: our powerful formulation is odor free so you won’t smell like medicine
•FAST RELIEF: it starts to go to work instantly
•MANUFACTURED IN THE USA: Purchase with confidence because Hempvana is manufactured in the USA in an FDA-inspected facility, safeguarded by GMP-certified practices
•#1 BRAND: We're proud to be America's #1 hemp pain brand, backed by 2022 AC Nielsen data

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$19.98

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Bengay

Bengay Lidocaine Pain Relief Cream, Maximum Strength OTC, Non-Greasy Topical Analgesic with 4% Lidocaine to Desensitize Nerves, Numbing Cream with a Soothing Jasmine Scent, 3 oz

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•TOPICAL PAIN RELIEF: 3-ounce tube of Bengay Lidocaine Topical Pain Relief Cream with a tropical jasmine scent for temporary relief of muscle and joint pain with numbing power to desensitize nerves
•POWERFUL LIDOCAINE CREAM: Bengay pain relief cream is made with maximum strength OTC 4% lidocaine HCI as an active ingredient to work to desensitize nerves and deliver numbing relief for muscle pain and joint pain
•DESENSITIZE NERVES: This soothing pain relief cream is formulated with a non-greasy formula, so it won't leave behind any residue. It can be used to help combat upper & lower back pain, neck pain, shoulder pain, knee pain, elbow pain, & joint pain
•LIGHT, PLEASANT SCENT: Bengay topical analgesic is formulated with a light tropical jasmine scent. Pack this convenient tube of lidocaine in your gym back or suitcase for relief of pain receptor nerves & muscle aches on the go
•MAXIMUM STRENGTH LIDOCAINE WITHOUT PRESCRIPTION FOR RELIEF: Adults and children 12 years and older, apply topical lidocaine numbing cream to the affected area no more than 3-4 times a day to help desensitize nerves and relieve muscle aches

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$8.87

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Thera Care

Thera Care Maximum Strength OTC Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 1.75 Oz

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
•FAST-ACTING LIDOCAINE — Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
•NON-GREASY FORMULA — Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
•SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
•Compare to Aspercreme with Lidocaine active ingredients
•1.75 oz. bottle (49.6g)
•Safety warning: For external use only. Do not use on large areas of the body or on cut, irritated or swollen skin, on puncture wounds, for more than one week without consulting a doctor
•Always read detailed instructions before use

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$3.99

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