Top 10 Best lice treatment shampoo in 2026

Last Updated - 6/25/2026

🏆Best Choice

RID

RID One & Done, Just One Application Head Lice Treatment, No Combing Required, Prescription Strength Ivermectin Lotion for Children & Adults, Eliminates Super Lice & Renders Eggs Non Viable

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•ONE & DONE LICE TREATMENT: Effectively treats head lice, super lice & eggs (nits) with just 1 application — No second application needed
•NO NIT COMBING REQUIRED: Clinically proven without the hassle of combing out nits (eggs)
•PRESCRIPTION STRENGTH: Powered by the original prescription strength ivermectin lotion 0.5%
•10 MINUTE TREATMENT: In just 10 minutes kills lice and leaves eggs (nits) non-viable
•PEDIATRICIAN RECOMMENDED: The active ingredient in this head lice treatment is endorsed by the American Academy of Pediatrics for treating super lice, which are tougher-to-kill lice that have built a resistance to traditional permethrin/pyrethroid lice treatments over time
•CHILD-SAFE FORMULA: Approved for use on children 6 months and up

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$34.98

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SO COZY

SO COZY Boo! Lice Scaring Shampoo For Kids Hair, Effective Lice Treatment (10.5 Fl Oz) Scare Away Lice with Tea Tree, Rosemary and Peppermint Oils, No Parabens, Sulfates, Synthetic Colors or Dyes

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Scares Away Lice: Our kid's lice shampoo is infused with essential oils to make sure lice don't go near your kids hair. It not only scares away lice but conditions too. A gentle formula with a fresh scent, to keep hair soft, healthy and lice-free
•Gentle, Nourishing Care: Tea Tree & Peppermint oils, Rosemary Extract & Keratin work together to provide lice prevention & protection. Scares away lice & protects hair. No mess, no fuss, just soft, shiny & healthy-looking lice free hair
•Kid-Friendly Formula: Expertly formulated especially for children's developing hair, So Cozy Kids lice shampoo that kills eggs and lice is formulated with natural and powerful lice repellents. Helps deter lice while it cleans and conditions
•No Nasty Ingredients: Cruelty free and free from Parabens, Sulfates, Phthalates, Formaldehyde, Synthetic Colors or Dyes, Propylene Glycol, Gluten, Wheat and Nuts that could irritate your child's sensitive skin
•Salon Quality Haircare: Get professional quality hair care for your kids from the comfort of your own home with So Cozy Kids Boo lice shampoo and lice treatment for kids. SoCozy has over 20 years of experience and expertise with kid's hair

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$8.66

$11.99

-28%

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Nix

Nix Ultra Superlice Treatment, All-in-One Shampoo, 4 Fl Oz & Lice Removal Comb

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Nix Ultra All-in-One Shampoo kills head lice and eggs (nits), including hard-to-kill superlice
•Nix Ultra Lice Comb assists in removing lice and eggs (nits) from hair after lice treatment
•Nix Ultra All-in-One Shampoo gently treats and cleanses hair with one-step easy application; no additional shampoo needed
•Nix Ultra Shampoo is safe for kids and is hypoallergenic, pesticide-free, non-toxic and does not contain parabens, colorants or dyes
•Nix is the number one pediatrician-recommended lice removal brand* * Based on Pediatrician Survey December 6, 2022

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$18.88

$19.99

-6%

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Nix

Nix Lice Treatment & Prevention Kit, All-in-One Shampoo, 4 fl oz, with Lice Removal Comb and Lice Prevention Daily Leave-in Spray, 6 fl oz

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•PESTICIDE-FREE TREAT & PREVENT KIT: The Nix Ultra Lice Treatment & Prevention Kit contains both the Nix Ultra All-in-One Shampoo that kills superlice, lice and eggs (also known as nits) and the Nix Lice Prevention Daily Leave-In Spray to keep your family protected from superlice & lice
•TREATS & CLEANS HAIR IN 10 MINUTES: The Nix Ultra All-in-One Shampoo gently treats and cleanses hair in only 10 minutes with a 1-step easy application, no additional shampoo required
•KILLS LICE WITHOUT COMBING: Includes Lice Removal Comb for convenience to assist in removing superlice, lice and eggs (nits) from hair after lice treatment
•DEFEND & REPEL SUPERLICE: The Nix Lice Prevention Daily Leave-In Spray defends and repels superlice & lice and provides long-lasting protection* to keep you and your family protected before, during and after treatment
•#1 PEDIATRICIAN RECOMMENDED BRAND*: Nix is the number one pediatrician-recommended lice removal brand that offers both treatment and prevention products; *Based on Pediatrician Survey December 31, 2024

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$28.98

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Licefreee Spray!

Licefreee Lice Spray for Kids Hair, Includes Professional Metal Nit & Lice Comb for Kids, Kills on Contact, 6 Fl Oz

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•LICE TREATMENT: Use this head lice treatment for kids . It includes our lice free spray for hair and nit comb to safely kill lice and nits. Safe for kids six months and older
•SUPER LICE KILLING: Sodium chloride, a naturally occurring mineral, targets and kills super lice, eggs, and nits, making this lice treatment effective without harsh chemicals
•SIMPLE APPLICATION: Hold the lice treatment spray 4-6 inches from the head, covering the scalp. Spray on dry hair and allow it to air dry, using the nit comb to complement the treatment
•PROFESSIONAL LICE COMB: Our lice kit includes a patented metal lice and nit comb for lice removal that extracts dead lice, nits, and eggs after the lice treatment.
•TRUSTED LICE SOLUTIONS: Since 1999, Licefreee has worked to expand our knowledge and range of hair products to address lice on hair, furniture, and bedding

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$9.97

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RID

RID Super Max Lice Treatment Kit, Kills Lice & Super Lice & Eggs + 24/7 Lice Defense, Pesticide Free, 3.4 FL OZ Solution + 6.8 FL OZ Daily Defense Shampoo & Conditioner + Nit Removal Comb

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•The Only 5 in 1 Lice Complete Lice Treatment Kit: 1) Kills Lice Fast 2) Even Kills Hard-to-Kill Super Lice 3) Kills Eggs 4) Blocks New Lice 5) Plus provides ongoing 24/7 lice defense upon return to school or camp.
•Kills Lice Better than the Leading Pesticide: Clinical testing shows that Rid Super Max is more effective at killing head lice than the leading pesticide ingredient.
•The advanced treatment solution is enhanced with lice defense ingredients to not only kill super lice and eggs but also to help keep new lice away from treated hair.
•Plus includes RID Daily Defense Shampoo & Conditioner to help keep lice away 24/7 upon return to school or camp (with daily use).
•100% effective at keeping lice away when Daily Defense Shampoo & Conditioner is used daily.
•No Harsh Chemicals & No Pesticides: It is tough on lice but gentle on kids.

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$24.40

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Vamousse

Vamousse Head Lice Defense Daily Shampoo, Use After Exposure or Treatment, Prevents Lice Infestation, No Parabens, Sulfates or Dyes, Family Size, 13.5 Oz

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•Daily Lice Defence: Vamousse Head Daily Defense Lice Shampoo is super effective in getting rid of residual lice after treatment and preventing further infestation. Use in place of regular shampoo after exposure to eliminate pesticide-resistant super lice.
•Powerful Ingredients: Eucalyptus globulus & natrum muriaticum are powerful pediculicides in this homeopathic lice prevention shampoo that effectively kills lice and eggs, while preventing undetected infestations. Tough on lice while being gentle on hair.
•Strikes Early: Don’t wait for the itch to start lice treatment! It can take 4-6 weeks for itching to start or to confirm exposure. By the time an infestation is identified, others have likely been exposed and may have contracted the infestation themselves.
•Safe to Use: This lice shampoo is free from harmful pesticides, toxins, parabens, sulfates, and dyes. Leave in hair for three minutes before rinsing with warm water. Formulated to be used daily for 10-14 days after suspected lice exposure
•For the Whole Family: This lice shampoo can be used by everyone, including children over the age of 2 years old. Perfect for school, summer camp or sleepovers, this shampoo protects the whole family from a possible lice outbreak.

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$16.49

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Fairy Tales

Fairy Tales Rosemary Repel Shampoo, 12 fl oz. & Conditioning Spray, 8 fl oz. Duo Kids Like the Smell, Lice Do Not

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•Rosemary Repel Shampoo and Conditioning Spray is the perfect combo to cleanse and detangle the hair, the added bonus is that the formulas contain essential oils that kids love the smell of, lice do not.
•In lab studies, our proprietary blend of rosemary, citronella, tea tree, geranium and peppermint oils also help defend against unwanted visitors.
•Jojoba, Chamomile and Lavender extracts hydrate, moisturize and soothe the scalp.
•Gentle enough for everyday use. No harsh chemicals or toxins.
•Sulfate-free, paraben free, phthalate free, gluten free, soy free, dairy free and nut free.

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$22.95

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HERKLIN

Herklin Lice Treatment Shampoo, Maximum Strength, Easy to Apply, 2 Fl Oz, Bottle

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Ensuring your family's well-being is undoubtedly a top priority. For this reason, I strongly suggest using Herklin Lice Treatment Shampoo. It not only delivers optimal results but is also suitable for all members of the family.
•We understand how frustrating it can be to deal with lice. That's why we offer "Maximum Strength" - a solution that prevents and eliminates them in three easy steps, allowing you to return to feeling your best.
•Herklin Shampoo has got you covered! We've included a specially designed nit comb to make the removal process as efficient as possible.
•In only ten minutes, you will undoubtedly be amazed by the remarkable effectiveness of this incredible formula!

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$8.23

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RID

RID Daily Defense Lice Shampoo & Conditioner, Used Daily Provides 24/7 Defense Against Head Lice, 100% Effective, 10.1 Ounce

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•Friendly to hair, Unfriendly to Lice: RID Daily Defense Shampoo & Conditioner cleans, conditions and smells like a regular, everyday shampoo & conditioner while also being 100% effective at keeping lice away.
•24/7 Lice Defense: Contains the Lice Defense Factor (LDF) to defend against head lice all day long.
•While some lice defense shampoos work only by repelling lice via scented oils, Rid Daily Defense uniquely works in 4 ways to keeps lice away. 1) Neutralizes the static charge in hair that attracts lice 2) Makes lice avoid hair 3) Impedes attachment 4) Stop lice from laying eggs in hair.
•Safe for the Whole Family: Contains no harsh chemicals, pesticides or alcohol.
•Use if there is a lice concern in your child's school or camp, after treating for lice to keep lice from returning, or to help prevent the spread of lice to siblings or other family members when there is a case of lice in the home.

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$12.98

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