Top 10 Best rid lice in 2026

Last Updated - 6/17/2026

🏆Best Choice

RID

RID One & Done, Just One Application Head Lice Treatment, No Combing Required, Prescription Strength Ivermectin Lotion for Children & Adults, Eliminates Super Lice & Renders Eggs Non Viable

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•ONE & DONE LICE TREATMENT: Effectively treats head lice, super lice & eggs (nits) with just 1 application — No second application needed
•NO NIT COMBING REQUIRED: Clinically proven without the hassle of combing out nits (eggs)
•PRESCRIPTION STRENGTH: Powered by the original prescription strength ivermectin lotion 0.5%
•10 MINUTE TREATMENT: In just 10 minutes kills lice and leaves eggs (nits) non-viable
•PEDIATRICIAN RECOMMENDED: The active ingredient in this head lice treatment is endorsed by the American Academy of Pediatrics for treating super lice, which are tougher-to-kill lice that have built a resistance to traditional permethrin/pyrethroid lice treatments over time
•CHILD-SAFE FORMULA: Approved for use on children 6 months and up

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$34.98

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Nix

Nix Lice Treatment Hair and Home Kit, Ultra Hair Solution (3.4 Fl Oz), Home Defense Bedbug and Lice Killing Spray (5 Fl Oz)

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•ALL-IN-ONE LICE REMOVAL KIT: The Nix Ultra Lice Removal Kit contains both the Nix Ultra Lice Treatment Solution to kill lice in hair and the Nix Lice Killing Spray to protect and kill lice & bedbugs within the home
•100% PESTICIDE-FREE SOLUTION: The Nix Ultra Lice Treatment Solution kills pesticide-resistant superlice, lice and eggs (also known as nits) – 1 application is more effective at killing lice than Ivermectin Lotion
•;
•in laboratory study vs. Nix Ultra Lice Treatment Solution
•KILLS LICE WITHOUT COMBING: Includes Lice Removal Comb for convenience to assist in removing superlice, lice and eggs (nits) from hair after lice treatment
•LICE & BEDBUGS HOME DEFENSE: The Nix Lice Killing Spray kills lice & bedbugs on furniture and bedding, effective for up to 4 weeks
•#1 PEDIATRICIAN RECOMMENDED BRAND*: Nix is the number one pediatrician-recommended lice removal brand that offers both treatment and prevention products; *Based on Pediatrician Survey December 31, 2024

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$18.60

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RID

RID Super Max Lice Treatment Kit, Kills Lice & Super Lice & Eggs + 24/7 Lice Defense, Pesticide Free, 3.4 FL OZ Solution + 6.8 FL OZ Daily Defense Shampoo & Conditioner + Nit Removal Comb

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•The Only 5 in 1 Lice Complete Lice Treatment Kit: 1) Kills Lice Fast 2) Even Kills Hard-to-Kill Super Lice 3) Kills Eggs 4) Blocks New Lice 5) Plus provides ongoing 24/7 lice defense upon return to school or camp.
•Kills Lice Better than the Leading Pesticide: Clinical testing shows that Rid Super Max is more effective at killing head lice than the leading pesticide ingredient.
•The advanced treatment solution is enhanced with lice defense ingredients to not only kill super lice and eggs but also to help keep new lice away from treated hair.
•Plus includes RID Daily Defense Shampoo & Conditioner to help keep lice away 24/7 upon return to school or camp (with daily use).
•100% effective at keeping lice away when Daily Defense Shampoo & Conditioner is used daily.
•No Harsh Chemicals & No Pesticides: It is tough on lice but gentle on kids.

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$21.89

$25.00

-12%

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RID

Rid Home Lice Bed Bug Dust Mite Spray Home Treatment Spray With Permethrin Kills Lice and Lice Eggs on Mattresses Furniture Car Interiors and Other Nonwashable Items Spray Can , 5 Ounce

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•Trusted Brand : RID is trusted by families for killing lice and lice eggs. This permethrin lice killing spray also kills bedbugs and dust mites.
•KILLS LICE AND THEIR EGGS: RID Home Lice, Bed Bug & Dust Mite Spray kills lice and their eggs on mattresses, furniture, car interiors, and other non-washable items.
•EFFECTIVE AGAINST BEDBUGS AND DUST MITES: RID Home Lice, Bed Bug & Dust Mite Spray is also effective at killing bedbugs and dust mites on non-washable items.
•WHERE TO USE: RID Home Lice, Bed Bug & Dust Mite Spray kills lice & their eggs on mattresses, furniture, car interiors, and other non-washable items.
•EASY TO USE: Just diffuse RID Home Lice, Bed Bug & Dust Mite Spray with permethrin for 3 seconds and allow to dry. Spray only on non-washable items such as mattresses, furniture, car interiors, and other items that cannot be laundered.

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$7.99

$9.99

-20%

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Nix

Nix Lice Treatment Family Pack, Kills Lice & Eggs, 2 Bottles Permethrin Crème Rinse (2 Fl Oz Each) & 2 Lice Combs

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Treat the whole family with maximum-strength Nix Creme Rinse to kill head lice and eggs (nits) in one easy application
•Prevents lice reinfestation for up to 14 days after initial application
•Nix Lice Creme Rinse is for use on head hair and is safe for use on children 2 months and older
•Nix Ultra Lice Comb assists in removing lice and eggs (nits) from hair after treatment
•Nix is the number one pediatrician-recommended lice removal brand* * Based on Pediatrician Survey December 6, 2022

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$14.27

$18.99

-25%

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RID

RID Daily Defense Lice Shampoo & Conditioner, Used Daily Provides 24/7 Defense Against Head Lice, 100% Effective, 10.1 Ounce

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•Friendly to hair, Unfriendly to Lice: RID Daily Defense Shampoo & Conditioner cleans, conditions and smells like a regular, everyday shampoo & conditioner while also being 100% effective at keeping lice away.
•24/7 Lice Defense: Contains the Lice Defense Factor (LDF) to defend against head lice all day long.
•While some lice defense shampoos work only by repelling lice via scented oils, Rid Daily Defense uniquely works in 4 ways to keeps lice away. 1) Neutralizes the static charge in hair that attracts lice 2) Makes lice avoid hair 3) Impedes attachment 4) Stop lice from laying eggs in hair.
•Safe for the Whole Family: Contains no harsh chemicals, pesticides or alcohol.
•Use if there is a lice concern in your child's school or camp, after treating for lice to keep lice from returning, or to help prevent the spread of lice to siblings or other family members when there is a case of lice in the home.

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$12.98

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RID

RID Super Max Advanced Shampoo Lice Removal Treatment, 3.4 Fl Oz, Includes Nit Removal Comb

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•Kills, cleans & defends in 1 easy shampoo.
•Kills both super lice & eggs while cleaning hair.
•Advanced formula is enhanced with lice defense ingredients to also help keep lice in your surroundings from re-entering treated hair.
•Pesticide-free, non-toxic and safe for use on children 1 years and older.
•Does not contain parabens, phthalates, alcohol, colorants or dyes.

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$18.88

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RID

RID Lice Treatment Complete Kit Includes Fluid Ounces Lice Killing Shampoo 2 Fluid Ounces Lice and Egg CombOut Spray Lice Comb and 3 Ounces Home Lice Bedbug Dust Mite Home Spray, 4 Piece Set, 1 Count

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•Proven Effective Treatment: For more than 10 years, RID Lice Killing Shampoo has been a proven, effective treatment for removing lice and their eggs
•KIT CONTAINS: one (1) 4 ounce bottle RID Lice Killing Shampoo, one (1) 2 ounce bottle RID Lice & Egg Comb Out Spray, one (1) RID lice comb and one (1) 3 ounce can Home Lice, Bed Bug & Dust Mite Spray
•SHAMPOO AND COMB OUT: RID Lice Killing Shampoo effectively treats lice while the RID Lice and Egg Comb Out Spray detangles hair to help make combining out lice and lice eggs easier; The included patented RID Lice Comb is specially designed to aid in removing lice eggs
•TREAT UNWASHABLE ITEMS: The RID Home Lice, Bedbug & Dust Mite Spray kills lice & their eggs on mattresses, furniture, car interiors and other non washable items

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$19.88

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RID

RID Super MAX 5-in-1: Hair & Home Complete Lice Treatment Kit, Kills Super Lice & Eggs in Hair & Home, 3.4 FL OZ Lice Shampoo + Nit Removal Comb + Home Lice Spray

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Comprehensive 5 in 1 Lice Complete Lice Treatment Kit for Hair & Home: 1) Kills Lice Fast 2) Even Kills Hard-to-Kill Super Lice 3) Kills Eggs 4) Provides immediate lice defense 5) Plus includes a breakthrough home control spray that kills even super lice and eggs on non-washable home surfaces.
•2X Faster Hair Treatment: The pesticide-free advanced shampoo in this kit provides 2X faster lice killing action than the leading pesticide-based treatment (permethrin 1% crème rinse).
•10X More Effective Home Control Spray: The RID Super MAX home control spray is over 10X more effective at killing lice than traditional permethrin 0.25% lice killing spray**.
•Why Is It More Effective? The dominant species of lice, called super lice, are resistant to traditional pesticide-based treatments like permethrin.
•Immediate Lice Defense: The advanced shampoo lice treatment is also enhanced with lice defense ingredients to help keep new lice away for up to 3 days.
•Home Control Spray is Safe for Use in Homes with Pets: The permethrin-free formula uses effective nature-based ingredients that not only provide superior efficacy but are also safe for use in homes with pets.
•Use RID SUPER MAX Home Control Spray on furniture, mattresses, car interiors, rugs, and other non-washable items. The spray has a light mint scent upon initial use. It will not stain water-safe fabrics and surfaces or leave a sticky residue.
•Kit contains a dual-action, pesticide-free SUPER MAX Advanced Shampoo, 100% Effective Nit Removal Comb, SUPER MAX Home Control Spray.

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$24.91

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RID

RID Super Max Sensitive Skin Lice Treatment, Kills Super Lice & Eggs, Safe for Sensitive Skin, Clinically Tested, Package Graphics May Vary

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•KILLS SUPER LICE & EGGS FAST: Kills in just 10 minutes.
•SAFE FOR SENSITIVE SKIN: Its hypoallergenic formula is made with natural ingredients that are safe for sensitive skin, without compromising effectiveness. It even helps calm an irritated scalp.
•CLINICALLY SHOWN TO KILL LICE BETTER than a leading chemical-based treatment while being gentle on skin
•CONTAINS: 1 bottle of Super Max Sensitive Skin 3.4 FL OZ solution and RID’s Nit Removal Comb to remove dead lice and eggs (nits). English & Spanish instructions are included inside. (Instrucciones en espanol incluidas en el interior.)

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$19.88

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