Top 10 Best eye drops for dry eyes in 2026

Last Updated - 6/19/2026

🏆Best Choice

Refresh

Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
•MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
•CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
•GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
•PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.

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$14.78

$15.75

-6%

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Refresh

Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary

9.6

ChoiceComparer.com Score

9.6

/ 10

Outstanding

Main highlights

•Original strength, preservative-free formula
•Relieves mild symptoms of eye dryness
•Instantly moisturizes and lubricates
•Designed to act like your own natural tears
•Great for sensitive eyes
•Value size. 50 on-the go, single-use vials
•Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
•The selling brand in preservative-free artificial tears. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

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$15.99

$21.99

-27%

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Alcon

Pataday Once Daily Relief Extra Strength Relief 2.5ml, 2 Count

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Eye allergy itch relief: works as an antihistamine to relieve itchy eyes in minutes
•Provides fast symptom relief: hinders allergic reactions by limiting the release of chemicals that cause inflammation
•Easy to use: one drop, use once daily
•All day relief: relief up to 24 hours
•Extra Strength relief: contains doctor-prescribed eye allergy itch relief ingredient

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$19.99

$37.99

-47%

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Systane

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

9.3

ChoiceComparer.com Score

9.3

/ 10

Excellent

Main highlights

•#1 Dr Recommended Brand of Artificial Tears*, packaging may vary
•Extended Protection
•Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
•Reduces both the signs and symptoms of dry eye
•Quickly soothe irritated eyes wherever you are

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$17.09

$25.49

-33%

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Systane

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Dr Recommended Brand of Artificial Tears
•Extended Protection
•Fast Long-Lasting Dry Eye Symptom Relief
•Reduces both the signs and symptoms of dry eye
•Quickly soothe irritated eyes wherever you are

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$5.48

$6.49

-16%

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TheraTears

TheraTears Extra Dry Eye Drops, Twin Pack, 2 Bottles x 0.5 fl oz (Pack of 1)

9.0

ChoiceComparer.com Score

9.0

/ 10

Great

Main highlights

•Immediate dry eye relief: TheraTears EXTRA Dry Eye Therapy lubricating eye drops provide immediate relief from dry eye symptoms; this formula delivers EXTRAordinary relief with up to 12 hours of hydrating comfort
•Instant hydration: TheraTears EXTRA eye drops restore eyes’ natural balance and deliver fast hydration relief for dry eyes, because hydration supports dry eye health
•Electrolytes: TheraTears eye drops’ unique formula contains OxyLytes, the 5 vital electrolytes found in natural tears
•Created by an ophthalmologist: The TheraTears formula was created by an ophthalmologist, following 18 years of research, for a one-of-a-kind eye drop
•Doctor-recommended: TheraTears is a doctor-recommended brand (per ProVoice Survey data collected 9/1/23-8/31/24), created to bring balance and hydration to dry eyes; your purchase may be FSA/HSA eligible, check your health plan for details

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$13.49

$21.99

-39%

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iVIZIA

iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•Your Dry Eyes Deserve Better: Thicker formula for overnight use, our gel provides more lubrication and moisture than our daytime formula and is ideal to relieve severe dry eye symptoms.
•Free of Irritating Preservatives: Sterile, preservative-free, and can be used before or after eye surgery.
•Sterile Single-Use Vials: iVIZIA Lubricant Eye Gel is offered in preservative-free sterile, single-use vials that are convenient and easy to use for severe dry eye or nighttime use.
•IVIZIA – We See a Better Way: for healthy, comfortable eyelids

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$17.95

$19.42

-8%

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Clear Eyes

Clear Eyes Sensitive Eyes Eye Drops – Gentle Relief for Red, Itchy, Dry Eyes, 12 Hours of Soothing Comfort, 0.5 Fl Oz

8.7

ChoiceComparer.com Score

8.7

/ 10

Good

Main highlights

•Clear Eyes Sensitive Eyes Drops provide gentle but effective relief of common sensitive eye symptoms
•Relieves redness for brighter, whiter eyes and provides up to 12 hours of soothing comfort
•Contains hyaluronate a gentle lubricant found naturally in the eye, helps provide longer duration of comfort
•Gentle relief of red, dry, itchy, gritty, irritated, burning and watery eyes
•No Benzalkonium Chloride

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$8.09

$8.99

-10%

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Visine

Visine Dry Eye Relief Lubricant Eye Drops, Artificial Tears with Polyethylene Glycol to Moisturize and Soothe Irritated, Gritty and Dry Eyes, Designed to Work Like Real Tears, 0.5 fl. oz

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•DRY EYE RELIEF: 0.5-fluid ounce bottle of Visine Dry Eye Relief Lubricant Dry Eye Drops to temporarily relief of burning and irritation due to dryness of the eye and for protection against further irritation
•DESIGNED TO WORK LIKE REAL TEARS: These sterile, moisturizing artificial tears provide soothing relief of dry, gritty and irritated eyes that can be caused by riding on an airplane, staring at a computer screen, or sitting in an air-conditioned room
•SOOTHING ACTIVE INGREDIENT: The hydrating drops lubricate eyes, feature polyethylene glycol 400 to help lubricate dry eyes and contains 10 ingredients found in your own natural tears
•GET DRY EYE RELIEF ANYWHERE: Available in a convenient & compact size, these sterile moisturizing eye drops fit easily in a purse, pocket, backpack or desk for effective symptom relief both at home & on-the-go
•60 YEARS OF EXPERIENCE: To use these eye drops from Visine, a brand backed by 60 years expertise, put one to two eye drops for dry, irritated eyes in the affected eye(s) as needed. For adults and children 6 years and older

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$7.98

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