Top 10 Best aleve pm extra strength in 2026

Last Updated - 6/27/2026

🏆Best Choice

Amazon Basic Care

Amazon Basic Care Naproxen Sodium Tablets 220 mg, Pain Reliever/Fever Reducer (NSAID), Muscular Aches, Backache, Headache, Toothache, Minor Arthritis Pain Relief & More, 300 Count (Packaging may vary)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets
•STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
•ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever
•ALL DAY RELIEF: Amazon Basic Care Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over
•CAPSULE-SHAPED TABLETS: This 12 hour pain reliever and fever reducer comes in a capsule-shaped tablet; this product is gluten free

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$9.67

$13.30

-27%

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Aleve

Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160 Count

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Up to 12-Hours of Uninterrupted Pain Relief: Aleve Pain Reliever & Fever Reducer Gelcaps provide long-lasting arthritis pain relief, as well as relief from muscular aches, backache, menstrual cramps, headache, toothache, and the common cold
•Easy Open Arthritis Cap: Specially designed arthritis bottle features an easy to open, cushionedcovered cap and contoured bottle for better control when your arthritis acts up. Package is not child-resistant
•Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
•Targeted Pain Relief: naproxen sodium relieves minor pain from arthritis
•Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
•Country of origin: India

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$25.17

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Aleve

Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 Count

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Up to 12-Hours of Uninterrupted Pain Relief: Aleve Back & Muscle Pain Relief Tablets provide long-lasting back pain and muscle pain relief
•Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
•Targeted Pain Relief: Every tablet is made with 220 mg of naproxen sodium to help you take on muscle pain and provide back pain relief
•Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
•Comes in small, easy-to-swallow tablets; use as directed

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$19.95

$24.99

-20%

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HealthA2Z

HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•500 mg Acetaminophen, a proven pain reliever, helps relieve muscle, joint, headache, and arthritis pain quickly.
•25 mg Diphenhydramine, a gentle, non-habit-forming sleep aid, helps you fall asleep and stay asleep while also relieving fever and minor aches and pain with the help of Acetaminophen.
•It contains NO Aspirin
•Adults and children 12 years and over: take 2 caplets at bedtime. Do not take more than 2 caplets of this product per 24 hours/ Children under 12 years do not use.
•No gluten added product

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$14.95

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Advil

Advil PM Liqui-Gels Minis, 80 Liquid Filled Capsules

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•One 80 count box of Advil PM Liqui-Gels Minis
•Smaller Capsule, Same Strength
•Fast-absorbing liquid-filled capsules
•Pain Reliever (NSAID) + Nighttime Sleep Aid
•Perfect for those who want the same strength in a more convenient size

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$17.98

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Advil

Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine HCL for a Sleep Aid - 40 Liquid Filled Capsules - Back to College

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•One bottle of 40 liquid filled capsules of Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine HCL for a Sleep Aid
•Ibuprofen PM pain medicine helps relieve occasional sleeplessness related to minor aches and pains, and by 2022, new packaging will feature 20% less plastic to keep nearly 500,000 pounds of plastic out of landfills
•Ibuprofen PM sleep aid and pain medication helps you fall asleep and stay asleep
•PM pain reliever that rushes liquid relief right where it hurts
•Headache relief, minor arthritis pain relief, back pain medicine and sleep aid for adults and children 12 years and older - the perfect addition to your college dorm room essentials
•Take two of these Advil pain reliever caplets at bedtime for occasional sleeplessness related to minor aches and pains
•HSA and FSA eligible product

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$7.88

$16.25

-52%

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Aleve

Aleve PM Sleep Aid Plus Pain Reliever Caplets, Naproxen Sodium & Diphenhydramine HCl, Nighttime, 120 Count

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•Say hello to a good night’s sleep with pain relief
•Aleve PM provides relief of occasional sleeplessness when associated with minor aches and pains
•Helps you fall asleep and stay asleep
•Sleep Aid plus 12 hour pain relieving strength of Aleve
•Contains diphenhydramine hydrochloride (nighttime sleep-aid) and naproxen sodium (pain reliever)
•Use as directed

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$19.13

$24.99

-23%

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Amazon Basic Care

Amazon Basic Care All Night Pain Relief PM, Naproxen Sodium, 220 mg/Diphenhydramine Hydrochloride, 25 mg Tablets, Pain Reliever/Nighttime Sleep-Aid, 160 Count

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•ACTIVE INGREDIENTS in this product are naproxen sodium 220 mg, a pain reliever, and diphenhydramine hydrochloride 25 mg, a nighttime sleep-aid. Compare to Aleve pm active ingredients.
•NAPROXEN SODIUM PM from Amazon Basic Care pairs diphenhydramine HCl 25 mg, a nighttime sleep-aid, with the 12-hour pain relief of naproxen sodium 220 mg to help you fall asleep and stay asleep.
•THE ACHES AND PAINS of the day can follow you into nighttime and prevent a good night's rest. The active ingredient naproxen sodium 220 mg is a NSAID (nonsteroidal anti-inflammatory drug) pain reliever.
•FALLING ASLEEP AND STAYING ASLEEP can be tough when aches and pains plague you in the nighttime. The active ingredient diphenhydramine hydrochloride 25 mg is a nighttime sleep-aid. Get the rest you need tonight for a better tomorrow.
•Amazon Basic Care NAPROXEN SODIUM PM CAPLETS: This nighttime product is for occasional sleeplessness associated with minor aches and pain for adults and children 12 years and over. capsule-shaped tablets

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$21.98

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Aleve

Aleve PM Pain Reliever Nighttime Sleep-Aid Caplets, 20 ea (Pack of 2)

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•LONG LASTING RELIEF: Two Aleve PM caplets help you fall asleep for a good night's rest and wake up refreshed and relieved from pain
•NIGHTTIME ALEVE PAIN RELIEVER: Pain relief caplets indicated for occasional sleeplessness associated with minor pains
•EFFECTIVE OVER‐THE‐COUNTER PM PRODUCT: Only Aleve PM combines a sleep aid and the 12‐hour pain relieving strength of Aleve
•CHILD‐RESISTANT PACKAGING: Aleve PM Pain Relief and Nighttime Sleep Aid come in a convenient, child‐ resistant bottle
•ALL NIGHT RELIEF: Two caplets can help you fall asleep and stay asleep to wake up refreshed and relieved from pain

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$19.27

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Aleve

Aleve Pain Relief and Nighttime Sleep Aid Naproxen Sodium Caplets ‐ 20 Count

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•LONG LASTING RELIEF: Two Aleve PM caplets help you fall asleep for a good night's rest and wake up refreshed and relieved from pain
•NIGHTTIME ALEVE PAIN RELIEVER: Pain relief caplets indicated for occasional sleeplessness associated with minor aches and pains
•EFFECTIVE OVER‐THE‐COUNTER PM PRODUCT: Only Aleve PM combines a sleep aid and the 12‐hour pain relieving strength of Aleve
•CHILD‐RESISTANT PACKAGING: Aleve PM Pain Relief and Nighttime Sleep Aid come in a convenient, child‐ resistant bottle
•ALL NIGHT RELIEF: Two caplets can help you fall asleep and stay asleep to wake up refreshed and relieved from pain

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$12.36

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