Top 10 Best ibuprofen pm in 2026

Last Updated - 6/24/2026

🏆Best Choice

Amazon Basic Care

Amazon Basic Care Ibuprofen Tablets, Fever Reducer and Pain Relief from Body Aches, Headache, Arthritis and More, Brown, 200 Count (Packaging may vary)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENT: This product contains ibuprofen 200 mg, a pain reliever and fever reducer (NSAID); compare to the active ingredient in Advil Ibuprofen Tablets
•PAIN RELIEVER AND FEVER REDUCER: Proven pain relief without a prescription for tough pain such as muscular aches, minor arthritis pain, toothache, backache, menstrual cramps or minor aches and pains from the common cold; also temporarily reduces fever
•STRONG RELIEF: Amazon Basic Care Ibuprofen Tablets 200 mg are strong on tough pain to help you get the relief you need to keep going; no prescription needed for this pain reliever and fever reducer
•EFFECTIVE: When pain tries to take over, turn to the proven pain relief of coated Amazon Basic Care Ibuprofen Tablets 200 mg; use for adults and children 12 years and over
•IBUPROFEN is the number one doctor recommended back pain OTC active ingredient (of U.S. physicians surveyed by an independent market research firm)
•Product may be manufactured in India or U.S.

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$4.67

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Amazon Basic Care

Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENT: This product contains ibuprofen 200 mg, a pain reliever and fever reducer (NSAID); compare to the active ingredient in Advil Ibuprofen TabletsPAIN RELIEVER AND FEVER REDUCER: Proven pain relief without a prescription for tough pain such as muscular aches, minor arthritis pain, toothache, backache, menstrual cramps or minor aches and pains from the common cold; also temporarily reduces fever
•STRONG RELIEF: Amazon Basic Care Ibuprofen Tablets 200 mg are strong on tough pain to help you get the relief you need to keep going; no prescription needed for this pain reliever and fever reducerEFFECTIVE: When pain tries to take over, turn to the proven pain relief of coated Amazon Basic Care Ibuprofen Tablets 200 mg; use for adults and children 12 years and over
•IBUPROFEN is the number one doctor recommended back pain OTC active ingredient (of U.S. physicians surveyed by an independent market research firm)
•Product may be manufactured in India or U.S.

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$8.79

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Amazon Basic Care

Amazon Basic Care Acetaminophen PM Caplets, Pain Reliever Plus Nighttime Sleep Aid, Extra Strength, Helps Occasional Minor Aches, Pains and Headache Relief, 100 Count, Packaging may vary

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENTS: The active ingredients in Amazon Basic Care Acetaminophen PM are acetaminophen 500 mg, pain reliever, and diphenhydramine HCl 25 mg, nighttime sleep aid. Compare to Extra Strength Tylenol PM Caplets active ingredients
•LESS PAIN, MORE SLEEP: Minor aches & pains can interfere with restful sleep. Amazon Basic Care Acetaminophen PM has 500 mg acetaminophen, pain reliever, and 25 mg of diphenydramine hydrochloride, nighttime sleep aid, together in easy-to-swallow caplets
•USE: Amazon Basic Care Acetaminophen PM may be used as a pain reliever and nighttime sleep aid for adults and children 12 years and over. Child-resistant cap.
•EFFECTIVE SLEEP AID: For pain with sleeplessness. Relieve minor pain with extra-strength Amazon Basic Care Acetaminophen PM nighttime sleep aid medicine which is aspirin free and gluten free.
•NON-HABIT FORMING: Extra strength Amazon Basic Care Acetaminophen PM Caplets are non-habit forming when used correctly.

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$5.97

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Amazon Basic Care

Amazon Basic Care Ibuprofen PM, Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg Tablets, Pain Reliever and Nighttime Sleep-Aid, 120 Count (Packaging may vary)

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•ACTIVE INGREDIENTS: This nighttime pain relief medicine contains ibuprofen 200 mg, a pain reliever (NSAID), and diphenhydramine citrate 38 mg, a nighttime sleep-aid; compare to Advil PM active ingredients
•NIGHTTIME SLEEP AID: Amazon Basic Care Ibuprofen PM contains a combination of a nighttime sleep-aid and a pain reliever (NSAID) that provides relief of occasional sleeplessness when associated with minor aches and painsPAIN RELIEF: Muscles, bones and joints are vulnerable targets for pain to attack; pain may begin with an injury or illness
•FOR ADULTS AND CHILDREN 12 YEARS AND OVER: Amazon Basic Care Ibuprofen PM tablets are used as a pain reliever (NSAID) and sleep aid for adults and children 12 years and over
•GLUTEN FREE: Amazon Basic Care Ibuprofen PM are coated caplets (capsule-shaped tablets) in a safety sealed bottle; this product is gluten free
•Product may be manufactured in India or U.S.

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$11.99

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Amazon Basic Care

Amazon Basic Care Ibuprofen PM, Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg Tablets, Pain Reliever and Nighttime Sleep-Aid, 20 Count

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•ACTIVE INGREDIENTS: This nighttime pain relief medicine contains ibuprofen 200 mg, a pain reliever (NSAID), and diphenhydramine citrate 38 mg, a nighttime sleep-aid; compare to the active ingredients of Advil PM
•NIGHTTIME SLEEP AID: Amazon Basic Care Ibuprofen PM contains a combination of a nighttime sleep-aid and a pain reliever/NSAID (nonsteroidal anti-inflammatory drug) that provides relief of occasional sleeplessness when associated with minor aches and pains
•PAIN RELIEF: Muscles, bones and joints are vulnerable targets for pain to attack; pain may begin with an injury or illness
•FOR ADULTS AND CHILDREN 12 YEARS AND OVER: Amazon Basic Care Ibuprofen PM tablets are used as a pain reliever (NSAID) and sleep aid for adults and children 12 years and over
•GLUTEN FREE: Amazon Basic Care Ibuprofen PM are coated caplets (capsule-shaped tablets) in a safety sealed bottle; this product is gluten free

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$3.99

$4.60

-13%

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HealthA2Z

HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•500 mg Acetaminophen, a proven pain reliever, helps relieve muscle, joint, headache, and arthritis pain quickly.
•25 mg Diphenhydramine, a gentle, non-habit-forming sleep aid, helps you fall asleep and stay asleep while also relieving fever and minor aches and pain with the help of Acetaminophen.
•It contains NO Aspirin
•Adults and children 12 years and over: take 2 caplets at bedtime. Do not take more than 2 caplets of this product per 24 hours/ Children under 12 years do not use.
•No gluten added product

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$14.95

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Advil

Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine HCL for a Sleep Aid - 40 Liquid Filled Capsules - Back to College

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•One bottle of 40 liquid filled capsules of Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine HCL for a Sleep Aid
•Ibuprofen PM pain medicine helps relieve occasional sleeplessness related to minor aches and pains, and by 2022, new packaging will feature 20% less plastic to keep nearly 500,000 pounds of plastic out of landfills
•Ibuprofen PM sleep aid and pain medication helps you fall asleep and stay asleep
•PM pain reliever that rushes liquid relief right where it hurts
•Headache relief, minor arthritis pain relief, back pain medicine and sleep aid for adults and children 12 years and older - the perfect addition to your college dorm room essentials
•Take two of these Advil pain reliever caplets at bedtime for occasional sleeplessness related to minor aches and pains
•HSA and FSA eligible product

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$7.89

$16.25

-51%

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Advil

Advil PM Pain Reliever And Nighttime Sleep Aid, Pain Medicine With Ibuprofen For Pain Relief And Diphenhydramine Citrate For A Sleep Aid - 120 Coated Caplets

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•One bottle of 120 coated caplets of Advil PM Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine Citrate for a Sleep Aid
•Ibuprofen PM sleep aid and nighttime pain reliever helps relieve occasional sleeplessness related to minor aches and pains
•Nighttime sleep aid and pain medication that helps you fall asleep and stay asleep
•Ibuprofen caplets are portable, so you can get a restful night's sleep whether you're at home or away - the perfect addition to your college dorm room essentials
•Advil ibuprofen sleep aid and PM pain medicine for adults and children 12 years and older
•Take two ibuprofen PM caplets at bedtime for minor arthritis pain relief, for headache pain relief and for occasional sleeplessness related to minor aches and pains
•HSA and FSA eligible product

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$17.13

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A+Health

A+Health Ibuprofen PM Softgels, Pain Reliever/Nighttime Sleep Aid (NSAID), 120 Count

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•ACTIVE INGREDIENTS: Contains active ingredients Ibuprofen 200mg (nonsteroidal anti-inflammatory drug) and Diphenhydramine 25mg—compare to the active ingredients in Advil PM Liquid-Gels
•NIGHTIME SLEEP AID: Provides relief from occasional sleeplessness when associated with minor aches and pains, helping you fall asleep and stay asleep
•TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor aches and pains due to headache, toothache, backache, menstrual cramps, the common cold, muscular aches, and minor pain of arthritis
•EASY TO SWALLOW: Softgels are liquid-filled capsules which can be easier to take for people who have difficulty swallowing
•GREAT VALUE: Fall asleep without aches and pains; Contains 120 softgels

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$14.02

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Advil

Advil PM Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine Citrate for a Sleep Aid - 80 Coated Caplets

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•One bottle of 80 coated caplets of Advil PM Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine Citrate for a Sleep Aid
•Ibuprofen PM sleep aid and nighttime pain reliever helps relieve occasional sleeplessness related to minor aches and pains, and by 2022, new packaging will feature 20% less plastic to keep nearly 500,000 pounds of plastic out of landfills
•Nighttime sleep aid and pain medication that helps you fall asleep and stay asleep
•Ibuprofen caplets are portable, so you can get a restful night's sleep whether you're at home or away - the perfect addition to your college dorm room essentials
•Ibuprofen sleep aid and PM pain medicine for adults and children 12 years and older
•Take two ibuprofen PM caplets at bedtime for minor arthritis pain relief, for headache pain relief and for occasional sleeplessness related to minor aches and pains
•HSA and FSA eligible product

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$20.43

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