Top 10 Best naproxen sodium in 2026

Last Updated - 6/23/2026

🏆Best Choice

Amazon Basic Care

Amazon Basic Care Naproxen Sodium Tablets, 200 Count (Pack of 1) (Packaging may vary)

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets
•STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
•ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever
•ALL DAY RELIEF: Amazon Basic Care Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over
•CAPSULE-SHAPED TABLETS: This 12 hour pain reliever and fever reducer comes in a capsule-shaped tablet; this product is gluten free

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$7.63

$9.86

-23%

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ALEVE

Aleve Liquid Capsules, Naproxen Sodium Capsules 220 mg (NSAID), Pain Reliever/Fever Reducer, Fast Pain Relief, 120 Count

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Aleve is Proven Stronger* & Longer on Pain than Tylenol *Based on clinical data from the first six hours after initial dosing.
•Just Two pills for all day pain relief. Each pill has the strength to last 12 hours.
•Get Fast, Continuous Pain Relief with Aleve Liquid Gels for up to 12 hours.
•Aleve is an over-the-counter (OTC), nonsteroidal anti-inflammatory drug (NSAID) designed to deliver up to 12 hours of continuous pain relief at the site of pain.

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$30.35

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GoodSense

GoodSense Naproxen Sodium Tablets, 220 mg, 400 Count

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENT: The active ingredient in GoodSense Naproxen Sodium Tablets, 220 mg is Naproxen Sodium; Compare to Aleve Caplets active ingredient
•STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours
•PAIN RELIEVER: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; Also temporarily reduces fever
•NAPROXEN SODIUM: A nonsteroidal anti-inflammatory drug (NSAID) used as a pain reliever/fever reducer
•FOR ADULTS AND CHILDREN 12 YEARS AND OLDER: Children under 12 years: ask a doctor

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$18.99

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Amazon Basic Care

Amazon Basic Care Naproxen Sodium 220 Mg Liquid Gels, Pain Reliever/Fever Reducer (NSAID), 180 Count (previously A+ health)

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•ACTIVE INGREDIENT: This pain reliever and fever reducer contains one 180 count bottle of active ingredient Naproxen Sodium 220mg (nonsteroidal anti-inflammatory drug); Compare to the active ingredient in Aleve Liquid Gels
•TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor pains due to headaches, toothaches, backaches, menstrual cramps, the common cold, muscular aches, and minor arthritis pain
•LIQUID-FILLED CAPSULES: Basic Care Naproxen Sodium capsules are liquid-filled capsules, which are easier to swallow and can provide rapid pain relief to get you back on track
•12 HOUR RELIEF: Strength to last 12 hours of relief from most common aches and pains at a great value
•ACHES AND PAINS: Don’t let aches and pain get in your way! This is a pain reliever and fever reducer for adults and children ages 12 years and over. Please see Drug Facts panel for full product details.

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$18.94

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HealthCareAisle

HealthCareAisle Naproxen Sodium, 220 mg - 200 caplets - Pain Reliever and Fever Reducer, Up to 12 Hours of Relief

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Naproxen Sodium caplets temporarily relieve minor aches and pains due to: minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache, the common cold; also temporarily reduces fever
•Comparable to the national brand: Has the same active ingredient as Aleve Caplets*
•Effective pain and fever relief for up to 12 hours
•See package label for warnings, directions and other important information; use only as directed
•HSA or FSA Eligible

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$9.50

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Amazon Basic Care

Amazon Basic Care Headache Pain Relief Naproxen Sodium Tablets 220 mg, Also Relieves Arthritis, Muscular Aches, Backache, Menstrual Cramps and Toothache, 90 Count

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Naproxen Sodium Tablets 220 mg, Headache Relief, is naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID). Compare to Aleve Headache Pain Tablets active ingredient.
•HEADACHE PAIN RELIEF and relief for ailments like minor pain of arthritis, backache, the common cold, muscular aches, menstrual cramps and toothache. Amazon Basic Care Naproxen Sodium Tablets 220 mg help you to keep going.
•LASTS 12 HOURS: Amazon Basic Care Naproxen Sodium Tablets 220 mg have the strength to last 12 hours with just one dose
•USE: Amazon Basic Care Naproxen Sodium Tablets 220 mg may be used as a pain reliever and fever reducer for adults and children 12 years and over
•GLUTEN FREE: Amazon Basic Care Naproxen Sodium Tablets 220 mg are a gluten free option for temporary relief of minor aches and pains as well as fever reduction

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$4.88

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A+Health

A+Health Naproxen Sodium 220 Mg Liquid Gels Back and Muscle Pain, Pain Reliever/Fever Reducer (NSAID), 180 Count

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•ACTIVE INGREDIENT NAPROXEN SODIUM: Contains active ingredient Naproxen 220mg (nonsteroidal anti-inflammatory drug) in an easy-to-swallow capsule—compare to the active ingredient in Aleve Back & Muscle Pain
•TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor pains due to backaches, menstrual cramps, and muscular aches, headaches, toothaches, the common cold, and minor arthritis pain
•LIQUID-FILLED CAPSULES: Our A+ Health Naproxen Sodium Back & Muscle Pain Capsules are liquid-filled capsules which can provide rapid relief and get you back on track
•12 HOUR RELIEF: Provides 12 hour relief from most common aches and pains at a great value; Contains 180 capsules
•EASY-TO-SWALLOW: Don’t let pain get in your way! Find fast-acting relief on-the-go with these easy-to-swallow capsules so you can get back to living

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$18.96

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CAMBER PHARMACEUTICALS, INC

Camber Naproxen Sodium, 220 mg - Pain Reliever and Fever Reducer (200 Count)

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in National Brand
•STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
•ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever
•ALL DAY RELIEF: Camber Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over

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$8.49

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HealthCareAisle

HealthCareAisle Naproxen Sodium, 220 mg - 225 caplets - Headache Pain Reliever, Up to 12 Hours of Relief

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Naproxen Sodium caplets temporarily relieve minor aches and pains due to: headache, minor pain of arthritis, muscular aches, backache, menstrual cramps, toothache, the common cold; also temporarily reduces fever
•Comparable to the national brand: Has the same active ingredient as Aleve Headache Pain Caplets*
•Effective pain and fever relief for up to 12 hours
•See package label for warnings, directions and other important information; use only as directed; HSA or FSA Eligible

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$11.05

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Aleve

Aleve Liquid Gels, Naproxen Sodium for Pain Relief ‐ 50 Count

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•LONG LASTING RELIEF: Each Aleve liquid gel has the strength to last up to 12 hours
•FEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces feverFEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces fever
•EFFECTIVE PAIN RELIEVER: Temporarily reduces fever and relieves minor pain of arthritis, muscular aches, backache, toothache, menstrual cramps, headache and the common cold
•CHILD‐RESISTANT PACKAGING: These Aleve Liquid Gels come in a child‐resistant bottle.
•DOCTOR RECOMMENDED: Aleve pain relief pills are the #1 orthopedic surgeon recommended OTC brand for minor arthritic pain

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$16.34

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