Top 10 Best medical mattress in 2026

Last Updated - 6/25/2026

🏆Best Choice

Vive

Vive Alternating Air Pressure Mattress Pad - The Original Bed Sore Prevention Solution - Hospital Topper for Bedridden Patients - Includes Waterproof, Breathable Ulcer Cushion & Whisper Quiet Pump

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•DOCTOR RECOMMENDED RELIEF FOR BED SORES & ULCERS: Providing relief from bed sores and ulcers that result from being bedridden, the alternating pressure mattress instantly promotes increased circulation and helps manage skin maceration. The variable pressure mattress evenly distributes weight and relieves pressure spots–instantly improving your loved one’s quality of life. Perfect for immobilized, bedridden patients who cannot shift their weight frequently.
•ADVANCED WAVE-LIKE THERAPY WITH 130 AIR CELLS: Our proprietary algorithm alternately inflates and deflates each of the pad’s 130 air cells, creating a mattress surface that evenly distributes a patient or loved one’s weight and instantly eliminates pressure spots. Each air cell is heat sealed to ensure it will not leak for exceptional durability.
•WHISPER-QUIET PUMP WITH CUSTOMIZABLE CONTROLS: Variable pressure pump is ultra-quiet for restful sleep. Producing constant air flow, the variable pump offers multiple levels of pressure for a customizable experience. Each pressure cycle is approximately six minutes long.
•TRUSTED DURABLE CONSTRUCTION SUPPORTS UP TO 300 LBS & IS WATERPROOF: Premium vinyl mattress supports up to 300 pounds. The waterproof mattress pad easily fits on an existing mattress or frame, with top and bottom flaps that tuck securely between the mattress and frame to prevent sliding. The included air hoses are flexible and non-binding for easy installation.
•FREE VIVE GUARANTEE: 1 year on pump and 60 days on mattress pad. Trust quality. Buy now with confidence.

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$79.99

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Drive Medical

Drive Medical FoamQuick'n Easy Comfort Mattress, Blue

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Foam Mattress: Active mattress replacement system provides comfort and support with its decompressing properties.General Note: Please allow 24 - 72 hours for your Mattress to regain its full shape. Any memory foam will expand faster in a warmer room. In cold temperature, at delivery, your mattress may take a bit longer to return to full sized from its compressed state.The expansion time of the mattress will vary as per the surrounding
•Convenient Design: The system has a non-slip bottom and 4 corner straps to keep this home bedding secure; two side carry handles make lifting and placement easy
•Durable Material: Removable Nylon stretch cover is fluid resistant, low shear and vapor permeable, helping protect the skin from friction and moisture
•Specifications: 80 inches in length x 36 inches in width x 8 inches in height; weight capacity: 275 lbs
•One Year Warranty: Buy with confidence from Drive Medical

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$144.99

$159.99

-9%

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Graham-Field

Lumex Select Hospital Bed Mattress, Multi-Layer Medical Foam, Fluid-Resistant, Twin XL, 35x80"

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Comfort That Supports You All Night – Two layers of premium foam provide targeted support and pressure relief, helping you wake up feeling refreshed and pain-free. Ideal for elderly users and those with limited mobility.
•Enhanced Pain Relief and Sleep Quality – Designed to reduce back, hip, and neck discomfort, this mattress conforms to your body and works with adjustable power bases for personalized comfort.
•Cooling Airflow for All-Night Comfort – Over 150 air pockets in the egg crate foam topper disperse heat, keeping you cool and comfortable throughout the night.
•Durable and Fluid-Resistant Cover – The vinyl and nylon zippered cover protects against leaks and spills while being easy to remove and clean — ensuring lasting peace of mind.
•Easy to Set Up and Use – The 35 x 80 x 6 inch mattress is rolled and compressed for convenient delivery and handling. Just unbox, unroll, and let it expand to its original shape.

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$199.99

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Invacare

Invacare Hospital Bed Mattress, Fluid-Resistant Removable Cover, Long Term Care Pressure Redistribution Medical-Grade Foam Mattress, 5 Fortress Shaped Cells, Made in The USA

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•Superior Pressure Relief with Fortress Shaped Cells: Features 5 unique Fortress Shaped Cells designed to reduce skin stress, enhance air flow, and provide targeted pressure relief for enhanced patient comfort during extended use.
•Fluid-Resistant & Easy-Clean Cover: Equipped with a medical-grade, washable, latex-free, tough-coated polyurethane cover featuring a flat concealed zipper, sewn/welded seams, and a nylon top/non-skid vinyl bottom—removable for effortless maintenance.
•Full Anti-Slip Design: Unlike competitors with limited coverage, our cover boasts a full anti-slip surface across the entire bottom, keeping the mattress securely in place on any hospital bed frame.
•High-Quality Construction: Built with a 1.8 density foam and 34 IFD firmness rating for optimal support and durability, ensuring long-lasting performance in medical settings.
•Proudly Made in the USA: Manufactured in the USA with a fire-protective layer, ensuring compliance with safety standards and premium quality you can trust.

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$179.99

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Invacare

Invacare Softform Premier Hospital Bed Mattress, 36" Wide x 80" Long, IPM1080

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•BEST SELLING MATTRESS: Features 2 independent layers a unique single-piece U-core and contoured foam insert which provides excellent patient comfort and optimizes pressure redistribution for patients up to Very High Risk
•PRESSURE INJURY PREVENTION: Individual foam cells allow superior patient immersion and pressure redistribution, helping reduce the risk of pressure injuries, all while supporting a 500 lb. weight capacity
•PREMIUM GRADE MATTRESS: The Softform Premier mattress 3-zone construction gives appropriate support of the head, mid-section, and foot sections of the mattress and is made of high density foam on both layers, providing superior support on the sides and base
•FLUID RESISTANT COVER: Fluid resistant four-way stretch polyurethane and feature a tough coated polyurethane base to extend the longevity of the mattress
•COMPATIBILITY & SPECIFICATIONS: The IPM1080 hospital style mattress is 36" wide x 80" long x 6" Thick. This mattress is compatible with a wide range of hospital beds, but is recommended to be used with the Invacare 5410IVC, or 5310IVC

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$376.00

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Drive Medical

Drive Medical 14893 Premium Guard Gel Mattress Overlay, Blue

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•Actual_Product_Weight - 47.8 lbs; Weight Capacity: 300-500 pounds
•Cover_Material - Fluid Resistant Nylon Top waterproof Vinyl Bottom.Wipe down the overlay with a damp cloth pre-soaked with warm water containing a mild detergent
•Features 15 gel bladders that cover entire patient contact area for the prevention and treatment of pressure ulcers
•Overall_Product_Height - 3.5"
•Overall_Product_Length - 76"

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$140.00

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Vaunn

Vaunn Medical Cloud Air Whisper Quiet Alternating Air Pressure Mattress Topper with Pump Twin Size 36" x 78" x 3"

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•#1 Doctor Recommended for the Relief of Body Ulcers & Bed Sores - Ideal for individuals on extended bed rest. It provides an effective sleep solution for patients with painful pressure ulcers.
•Revolutionary Air-Lift Technology - Effectively distributes constant airflow throughout the body to help increase circulation, relieve pressure spots, and prevent skin maceration.
•Advanced Sleep Wave Therapy - Consists of 130 pre-programmed air cells that gently inflate and deflate in a proprietary algorithm to eliminate pressure and distribute the user’s weight. Gentle wave-like therapy works to relax your muscles, promote blood circulation, and provide a cool sleep surface for optimum comfort.
•Whisper Quiet Pump with Customizable Controls – Equipped with a high-efficiency, low-noise pump designed for continuous 24-hour use. Now includes enhanced setup instructions, step-by-step troubleshooting guidance, and quick-start diagrams to ensure smooth operation right out of the box. Adjustable pressure settings allow users or caregivers to tailor firmness and airflow levels for maximum relief and comfort.
•Durable Waterproof Construction – U.S. Power Plug (110V) – Each air cell is pre-treated and heat-sealed to ensure mattress integrity. The medical-grade vinyl topper is waterproof, easy to clean, and fits most beds, supporting up to 300 lbs. This unit includes a standard U.S. 110V power plug and is intended for use with American outlets only. Size: 36" x 78" x 3" (when fully inflated). Includes top and bottom flaps to secure to bed.

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$57.99

$65.99

-12%

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Drive Medical

Drive Medical 14027 Med-Aire Low Air Loss Mattress Replacement System with Alternating Pressure, Dark Purple

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•Medical Air Mattress: Active mattress replacement system provides both alternating pressure and low air loss to optimize pressure redistribution, shear/friction reduction, and microclimate control
•20 Individual Cells: Air bed system includes 20 individually replaceable 8-inch air bladders to maximize immersion and envelopment; includes pillow feature for head stability and comfort
•Durable Material: Alternating pressure mattress features removable 4-way stretch PU cover is fluid resistant, low shear and vapor permeable, helping protect the skin from friction and moisture
•Audio and Visual Alarm: Automatically alerts when air pressure is low
•Specifications: 80 inches in length x 36 inches in width x 8 inches in height; pump airflow: 8 LPM; control unit cycle time: 10 minutes; weight capacity: 350 lbs

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$416.90

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VEVOR

VEVOR Hospital Bed Mattress, 300 lbs Load, Long Term Care Pressure Redistribution Medical-Grade Dual Layer Foam Mattress, Waterproof for Bedsore Treatment Nursing Homes and Home Care, 34 x 76 x 3.5 in

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Comfortable Support: Our hospital bed mattress features dual-layer high-density foams with gel infused – soft, cushioning top and firm, supportive bottom. It hugs your body, reducing discomfort from prolonged lying and improving sleep comfort
•Even Pressure Distribution: The built-in gel pads adapt to the body's shape for even pressure distribution and assist in regulating temperature. This hospital mattress helps prevent bedsores and protects sensitive skin for easier care
•Waterproof and Stain-Resistant Cover: Premium waterproof nylon cover resists spills and stains, keeping your medical bed mattress easy to clean. The zippered bottom makes it a breeze to swap out, while the breathable fabric keeps things cool
•Stays Put, No Slips: The slip-resistant base with non-slip mesh keeps the medical mattress securely in place. It comes with securing straps for stable attachment to beds or use on mattresses and won't slide around when repositioning or moving
•Ideal Care Mattress: At 76 x 34 x 3.5 inches with a 300 lbs weight capacity, this foam medical mattress fits hospital beds, rehab centers, and home care setups. Ships vacuum-compressed – just unroll and let it expand for 48 hours for optimal support

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$138.90

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Drive Medical

Drive Medical 15019 Therapeutic Foam Mattress, White

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•Foam Mattress: Therapeutic mattress replacement system provides pressure redistribution and shear/friction reduction
•Therapeutic Design: The horizontal cross-cut foam works to provide pressure redistribution in 5 therapeutic pressure zones; the non-skid bottom provides extra security
•Durable Material: Removable nylon stretch cover is fluid resistant, low shear, and vapor permeable, helping protect the skin from friction and moisture
•Non-Skid Bottom: Helps mattress stays safely in place
•Specifications: 80 inches in length x 35 inches in width x 5.5 inches in height; weight capacity: 350 lbs

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$174.00

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