Top 10 Best tissue box in 2026

Last Updated - 6/12/2026

🏆Best Choice

Kleenex

Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box, 3-Ply, Packaging May Vary

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•WHAT'S INCLUDED — 8 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 80 tissues per box (640 tissues total)
•FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
•SILKY SOFTNESS— These facial tissues are made with 3 layers of silky-soft strength that’s gentle on watery eyes and runny noses for an extra bit of comfort when you need it
•ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
•SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
•THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

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$16.51

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Kleenex

Kleenex Ultra Soft Facial Tissues, 4 Cube Boxes, 60 Tissues per Box, 3-Ply (240 Total), Packaging May Vary

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•WHAT'S INCLUDED — 4 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 60 tissues per box (240 tissues total)
•FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
•SILKY SOFTNESS— These facial tissues are made with 3 layers of silky-soft strength that’s gentle on watery eyes and runny noses for an extra bit of comfort when you need it
•ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
•SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
•THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)

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$6.58

$7.49

-12%

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Puffs

Puffs Ultra Soft Non-Lotion Tissues, 10 Cubes, 56 Tissues Per Box

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•Pack includes 10 Cube Boxes (56 Tissues Per Box) of Puffs Ultra Soft Facial Tissues
•Perfect size to stash anywhere
•Gentle on sensitive skin
•Made with cushiony thickness
•Comforts needy noses
•Dermatologist tested to be gentle on skin
•A nose in need deserves MORE Puffs indeed! MORE boxes so you don't run out.
•Sniffles and sneezes can come when you least expect, keep Puffs within reach to always protect.

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$13.20

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Puffs

Puffs Ultra Soft Facial Tissues, 4 Mega Cube Box, 72 Facial Tissues Per Box

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•Pack includes 4 Mega Cubes (72 Tissues Per Cube) of Puffs Ultra Soft Facial Tissues
•Perfect size to stash anywhere
•Gentle on sensitive skin
•Made with cushiony thickness
•Comforts needy noses

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$5.97

$8.99

-34%

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Puffs

Puffs Ultra Soft Non-Lotion Facial Tissues, 1 Cube, 48 Tissues Per Box

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Pack includes 1 Cube (48 Tissues Per Cube) of Puffs Ultra Soft Facial Tissues
•Perfect size to stash anywhere
•Gentle on sensitive skin
•Made with cushiony thickness
•Comforts needy noses
•Dermatologist tested to be gentle on skin
•A nose in need deserves MORE Puffs indeed! MORE boxes so you don't run out.
•Sniffles and sneezes can come when you least expect, keep Puffs within reach to always protect.

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$2.49

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Kleenex

Kleenex Lotion Facial Tissues with Coconut Oil, 4 Cube Boxes, 60 Tissues Per Box, 3-Ply

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•WHAT'S INCLUDED — 4 boxes of Kleenex Lotion 3-Ply Facial Tissues with Coconut Oil & Aloe, 60 tissues per box (240 tissues total)
•BE PREPARED FOR SICK DAYS — We know we can't prevent sick days, but Kleenex can help you through them by moisturizing your skin to help prevent skin irritation
•3 BENEFITS IN 1 TISSUE — Kleenex lotion facial tissues are designed to soothe and moisturize skin while protecting your hands, offering comprehensive care in every sheet
•SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
•MADE WITH LOTION— These facial tissues are dermatologist-tested and infused with coconut oil and aloe
•PERFECT FOR ANY HOME — Our Kleenex tissues boxes come in various stylish designs that complement your home décor (packaging may vary)

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$6.58

$7.49

-12%

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Presto!

Amazon Brand - Presto! Ultra-Soft 3-Ply Premium Facial Tissues, 264 Count (4 Packs of 66), (Packaging May Vary)

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•Packaging may vary
•IN THE BOX: 4 Cube Boxes of facial tissues with 66 3-ply tissues in each box
•ULTRA SOFT: Premium facial tissues offer durable strength and ultra softness
•FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
•FUN & COLORFUL: Eye-catching colors and designs; cube box color combinations may vary
•USE ANYWHERE: Ideal for bathrooms, living rooms, bedrooms, offices, classrooms and more

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$4.93

$5.43

-9%

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Presto!

Amazon Brand - Presto! Ultra-Soft 3-Ply Premium Facial Tissues, 1188 Count (18 Packs of 66), (Packaging May Vary)

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•Packaging may vary
•IN THE BOX: 18 Cube Boxes of facial tissues with 66 3-ply tissues in each box (1188 total)
•ULTRA SOFT: Premium facial tissues offer durable strength and ultra softness
•FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
•FUN & COLORFUL: Eye-catching colors and designs; cube box color combinations may vary
•USE ANYWHERE: Ideal for bathrooms, living rooms, bedrooms, offices, classrooms and more

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$18.26

$19.92

-8%

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Amazon Basics

Amazon Basics Facial Tissue with Lotion, 2-Ply, 300 Count (4 Packs 75), (Packaging may vary)

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Packaging may vary
•IN THE BOX: 4 cube boxes; 75 tissues per cube (300 tissues total)
•SOFT AND GENTLE: 2-ply white facial tissues infused with lotion for extra comfort
•FSC-CERTIFIED FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
•USE ANYWHERE: perfect for bathrooms, living rooms, bedrooms, offices, classrooms
•STYLISH VARIETY: Cube color combinations may vary

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$7.15

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Amazon Basics

Amazon Basics Facial Tissue with Lotion, 2-Ply, 1350 Count (18 Packs of 75), (Packaging May Vary)

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•Packaging may vary
•IN THE BOX: 18 cube boxes; 75 tissues per cube (1,350 tissues total)
•SOFT AND GENTLE: 2-ply white facial tissues infused with lotion for extra comfort
•FSC-CERTIFIED SKIN FACIAL TISSUE (FSC N004130): Made with materials from well-managed forests, recycled materials, and/or other controlled wood sources
•USE ANYWHERE: perfect for bathrooms, living rooms, bedrooms, offices, classrooms
•STYLISH VARIETY: Cube color combinations may vary

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$28.97

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Our team evaluates this data alongside genuine user feedback, merging AI analysis with human insights to provide you with real-time, highly-rated recommendations that empower your decision-making with clarity and confidence.