Top 10 Best triple antibiotic ointment with pain relief in 2026

Last Updated - 6/25/2026

🏆Best Choice

Globe

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•INFECTION PROTECTION: Globe Triple Antibiotic Ointment helps to soothe painful cuts, scrapes, and burns while preventing infection. 100% Infection Protection!! Healing Ointment
•FIRST AID KIT: Globe Triple Action Antibiotic ointment is a must have product in your first aid kit. Its a skin care treatment for minor cuts, scrapes, and burns. Frist class First Aid Treatment for Minor Cuts, Scars, Eczema, Scraps, and Burns. Perfect Healing Ointment for your First Aid Cabinet.
•VALUE PACK: Globe Triple Antibiotic Ointment Value Pack comes with 4 single 1 oz tubes. The Globe Triple Antibiotic Value pack includes 4 individual tubes (1 oz each- a total of 4 oz) to take with you anywhere.
•EASY TO TAKE WITH YOU: Keep Globes Triple Antibiotic Ointment 4 tubes Value Pack in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carryon luggage. The convenience of the tube size can go with you anywhere.
•WHATS INSIDE: Globe Triple Antibiotic Ointment contains the same active antibiotic ingredients as the leading name brand: neomycin, bacitracin and polymyxin. It provides 24-hour protection against infection in minor cuts scrapes and burns.
•QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. US FDA audited manufacturing facilities. Trifecta Pharmaceuticals USA is a family business based in sunny Fort Lauderdale, Florida USA.

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$7.32

$12.99

-44%

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Bactine

Bactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz

9.6

ChoiceComparer.com Score

9.6

/ 10

Outstanding

Main highlights

•MAX RELIEF FOR PAIN & ITCH: Bactine MAX is an all-in-one antibiotic ointment that relieves pain & kills germs from minor cuts, scrapes, burns & bug bites
•ANTIBIOTIC OINTMENT: 24 hour infection protection. Our first aid healing ointment is made with Bacitracin for killing germs fast to keep you protected
•NO-STING & NO WORRIES: Formulated with 4% lidocaine, the maximum amount allowed for OTC topical anesthetic. Unlike hydrogen peroxide, his antibiotic cream treats minor wounds, bug bites, and burns without a painful, harsh sting
•FIRST AID KIT MUST HAVE: Accidents happen, be prepared. Keep your first aid supplies stocked with Bactine MAX. Whether it’s a scraped knee, blistered heel or itchy bug bite, this anti-itch, pain relief first aid ointment provides cooling relief where you need it most
•TRUSTED FOR OVER 70 YEARS: With a legacy spanning over 70 years, Bactine has been the go-to choice for families seeking the best first aid available. Safe for adults and children 2 years old plus

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$4.97

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Amazon Basic Care

Amazon Basic Care First Aid Antibiotic Burn Relief, Maximum Strength Triple Antibiotic Ointment, 1 ounce (pack of 1)

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•ACTIVE INGREDIENTS: Amazon Basic Care First Aid Antibiotic + Burn Relief contains these active ingredients: Bacitracin Zinc; Neomycin Sulfate; Polymyxin B Sulfate; & Pramoxine HCl. Compare to the active ingredients in Neosporin + Burn Relief.
•PROTECTS AGAINST INFECTION: Triple antibiotic ointment infection protection is combined with pain relief for burns and for minor wounds. Make room in your first aid kit for this maximum strength antibiotic ointment with pain relief.
•FIRST AID TRIPLE ANTIBIOTIC OINTMENT WITH PAIN RELIEF: When minor cuts, scrapes and burns occur, you look for maximum strength pain relief. Amazon Basic Care First Aid Antibiotic + Burn Relief ointment combines three antibiotics and an external analgesic to relieve minor burn pain plus infection protection.
•MAXIMUM STRENGTH: No matter how careful we are, minor cuts, scrapes and burns may occur, so be prepared. This ointment helps with triple antibiotic infection protection plus burn relief.
•FOR ADULTS AND CHILDREN ages 2 years and older, Amazon Basic Care First Aid Antibiotic + Burn Relief is a triple antibiotic ointment with maximum strength pain relief and infection protection plus burn relief. For children under 2 years of age, ask a doctor.

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$5.61

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CareAll

CareAll Triple Antibiotic Ointment + Pain Relief 1.0 oz (4 Pack), Dual Action First Aid for Minor Scrapes, Cuts, and Burns to Help Prevent Infection While Providing Maximum Strength Pain Relief.

9.3

ChoiceComparer.com Score

9.3

/ 10

Excellent

Main highlights

•FIRST AID PLUS PAIN RELIEF Triple Antibiotic Ointment for the prevention of infections in minor cuts, scrapes and burns while providing maximum strength pain relief.
•FORMULATED with you in mind. CareALL Triple Antibiotic plus pain relief ingredients are phthalate-free, paraben-free, dye-free, and fragrance-free.
•ACTIVE INGREDIENTS Compare to the Active Ingredients to Leading Brand. Active Ingredients (in each gram): Bacitracin Zinc 500 Units, Neomycin Sulfate 3.5mg, Polymyxin B Sulfate 10,000 units, Pramoxine HCI 10mg
•TAMPER PROOF each 1oz Tube has a tamper evident foil safety seal for your safety.
•FDA REGISTERED with NDC# (National Drug Code Number) printed on packaging with LOT # and Expiration Date. For External Use Only.

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$9.99

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Neosporin

Neosporin + Lidocaine First Aid Antibiotic Ointment, Maximum Strength & Fast-Acting Topical Pain Reliever, 24-Hour Infection Protection That Numbs Away The Pain, Bacitracin Zinc, 0.5 oz

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•0.5-ounce tube of Neosporin + Lidocaine Pain Relieving Antibiotic Ointment for first aid wound care of minor cuts, scrapes, and burns
•Topical antibiotic ointment provides 24-hour infection protection of minor wounds and helps to reduce pain with maximum-strength, fast-acting lidocaine to numb the area
•Contains bacitracin zinc, neomycin sulfate and polymyxin B sulfate antibiotics to help prevent wound infection of minor cuts, scrapes, and burns and fast-acting lidocaine as an external analgesic for maximum-strength numbing and pain relief
•The antibiotic ointment from the #1 doctor recommended brand not only helps fight infection for 24 hours, but also numbs away the pain, making it a great addition to your first-aid kit and wound care supplies
•For best results, clean the affected area, apply a small amount of the topical antibiotic and pain relief numbing ointment 1 to 3 times daily, and cover with a sterile bandage

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$8.28

$11.11

-25%

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CareAll

CareAll Triple Antibiotic Ointment + Pain Relief 1.0 oz (2 Pack), Dual Action First Aid for Minor Scrapes, Cuts, and Burns to Help Prevent Infection While Providing Maximum Strength Pain Relief.

9.0

ChoiceComparer.com Score

9.0

/ 10

Great

Main highlights

•FIRST AID PLUS PAIN RELIEF Triple Antibiotic Ointment for the prevention of infections in minor cuts, scrapes and burns while providing maximum strength pain relief.
•FORMULATED with you in mind. CareALL Triple Antibiotic plus pain relief ingredients are phthalate-free, paraben-free, dye-free, and fragrance-free.
•ACTIVE INGREDIENTS Compare to the Active Ingredients to Leading Brand. Active Ingredients (in each gram): Bacitracin Zinc 500 Units, Neomycin Sulfate 3.5mg, Polymyxin B Sulfate 10,000 units, Pramoxine HCI 10mg
•TAMPER PROOF each 1oz Tube has a tamper evident foil safety seal for your safety.
•FDA REGISTERED with NDC# (National Drug Code Number) printed on packaging with LOT # and Expiration Date. For External Use Only.

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$6.49

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MED PRIDE

MED Pride Triple Antibiotic Pride Ointment Tube 1 Oz 4-Pack, First Aid for Minor Wounds, Scratches, Abrasions, with Zinc, Neomycin, Polymyxin

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•HEALING PROWESS: Experience the healing prowess of triple antibiotics ointment, a must-have for any first aid kit. Designed to treat minor wounds, scratches, and abrasions, this triple-antibiotic ointment ensures minor injuries don't escalate into major health concerns.
•POTENT BLEND: Harness the power of this nonprescription antibiotic, a potent blend of Zinc, Neomycin, and Polymyxin. This triple antibiotic cream works synergistically to reduce inflammation, and promote skin regeneration.
•CONVENIENT 4-PACK: Enjoy the convenience of a 4-pack of triple antibiotic cream maximum strength, ensuring you're always prepared. Keep a tube of this antibiotics ointment in various locations such as your home, car, or office for easy access.
•24-HOUR PROTECTION: Trust in the long-lasting protection of this ointment , providing 24-hour defense . Especially crucial in the first hours after an injury, this triple antibiotic ointment continuously shields your wound from potential infection.
•QUALITY TRUST: Place your trust in the quality and safety of MED PRIDE, a brand committed to delivering top-notch antibiotics. This ointment offers reliable and effective wound care, making it a trusted choice for antibiotics for humans.

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$7.29

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Globe

Globe (4 Pack Triple Antibiotic + Pain Relief Ointment 1oz, First Aid Antibiotic, Soothes Pain, Cuts, Burns and Scrapes 24 Hour Infection Protection

8.7

ChoiceComparer.com Score

8.7

/ 10

Good

Main highlights

•FIRST AID ANTIBIOTIC + PAIN RELIEF Ointment: Globe Dual-Action Ointment comes in a convenient sealed tube for high powered first aid wound care for minor cuts, scrapes, and burns.
•FIRST AID KIT: Globe Dual-Action Ointment is a must have product for your first aid kit. helps fight infection for 24 hours, but also soothes & reduces pain, making it a great addition to your first-aid kit and wound care supplies.
•INGREDIENTS: Globe Dual-Action Ointment contains the same active antibiotic ingredients as the leading First Aid Antibiotic Plus Pain Relief Name Brand: Neomycin Sulfate, Polymyxin B Sulfate, Bacitracin, and Pramoxine precisely formulated in a Cream base to provide powerful 24-hour Infection Protection and Pain Relief.
•EASY TO TAKE WITH YOU: Keep Globes Dual-Action Ointment in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carry on luggage. The convenience of the tube size can go with you anywhere.
•EASY TO TAKE WITH YOU: Keep Globes Dual-Action Ointment in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carry on luggage. The convenience of the tube size can go with you anywhere.

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$9.88

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Globe

(2 Pack) Globe 1oz Triple Antibiotic Ointment + Pain Relief, Dual Action Maximum Strength First Aid Ointment Soothes and Heals Painful Minor Scratches and Wounds and Prevents Infection

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•FIRST AID ANTIBIOTIC Ointment: Globe Dual-Action Ointment comes in a convenient sealed tube for high powered first aid wound care for minor cuts, scrapes, and burns.
•FIRST AID KIT: Globe Dual-Action Ointment is a must have product for your first aid kit. helps fight infection for 24 hours, but also soothes & reduces pain, making it a great addition to your first-aid kit and wound care supplies.
•INGREDIENTS: Globe Dual-Action Ointment contains the same active antibiotic ingredients as the leading First Aid Antibiotic Plus Pain Relief Name Brand: Bacitracin, Neomycin Sulfate, Polymyxin B Sulfate, and Pramoxine precisely formulated in a Cream base to provide powerful 24-hour Infection Protection and Pain Relief.
•QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. Trifecta Pharmaceuticals USA, manufacturers the Globe Brand
•EASY TO TAKE WITH YOU: Keep Globes Dual-Action Ointment in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carry on luggage. The convenience of the tube size can go with you anywhere.

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$5.99

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